Seat No.:
Subject Code: 2240003
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 4 EXAMINATION - WINTER -2019
Subject Name: Pharmaceutical Chemistry — V (Biochemistry — IT)
Time: 02:30 PM TO 05:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) Define Amino acid. Classify amino acid on the basis of structure. 06
- (b) Discuss the Secondary Structure of Protein. 05
- (c) Write a note on Structure of RNA. 05
- (a) Discuss the Initiation, Elongation and Termination of Protein Biosynthesis. 06
- (b) Write a note on Denaturation of Protein. 05
- (c) Define Porphyrin and Give the Biosynthesis of Heme. 05
- (a) Write a note on ETC. 06
- (b) Discuss the Enzyme involve in Biological oxidation. 05
- (c) Write a note on Inhibitors of Oxidative Phosphorylation. 05
- (a) Write a note on Oxidative Phosphorylation. 06
- (b) Discuss the Concept of Free energy. 05
- (c) Discuss the DNA repair mechanism. 05
- (a) Discuss the Transamination and Deamination in detail. 06
- (b) Discuss the synthesis of RNA from DNA template. 05
- (c) Write a note on Genetics Code. 05
- (a) Give the Reaction of Urea Cycle and discuss the metabolic disorder of Urea Cycle. 06
- (b) Give the reaction of Pyrimidine biosynthesis. 05
- (c) Discuss the Lac-Operon Concept. 05
- (a) Give the reaction of Purine nucleotides. 06
- (b) Write a note on DNA Replication. 05
- (c) Discuss the Southern Blotting technique as an analytical tool for identification of nucleic acid. 05
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Total Marks: 80
Date: 20-12-2019
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