Download GTU B.Pharma 2019 Winter 4th Sem BP404TP Pharmacology I Question Paper

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1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

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1. (a) Write a note on Sources of drugs. 06
   (b) Define following terms: 1) Pharmacology 2) Agonist 3) Drug tolerance 4) Allergy 5) Idiosyncrasy 05
   (c) Describe synthesis and metabolism of adrenergic neurotransmitter. 05
2. (a) Explain merits and demerits of parental route. 06
   (b) Enlist factors affecting oral drug absorption. 05
   

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   (c) Classify parasympathomimetic agents with example. Write a note on pilocarpine. 05
3. (a) Describe zero order and first order kinetic of drug elimination. 06
   (b) Explain the enzyme induction and inhibition. 05
   (c) Write a note on G protein coupled receptors. 05
4. (a) Describe various phases of clinical trial and its importance. 06
   

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   (b) Write a note on Adverse drug reaction. 05
   (c) Classify sedative-hypnotic agents. Describe in detail barbiturates. 05
5. (a) Differentiate between sympathetic and parasympathetic nervous system. 06
   (b) Describe the different stages of anesthesia. 05
   (c) Describe the pharmacology of Acetylcholine. 05

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6. (a) Describe the pharmacological actions of Ethyl alcohol. 06
   (b) Classify types of epilepsy. Describe phenytoin in detail. 05
   (c) Elaborate following terms with examples a) drug addiction and b) drug dependence. 05
7. (a) Describe pharmacology of opioid analgesics. 06
   (b) Write a note on CNS stimulant agents. 05
   

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   (c) What are preanesthetic agents? How they are useful? 05