Download GTU B.Pharma 2019 Winter 7th Sem 2270002 Pharmaceutical Technology I Question Paper

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GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm - SEMESTER- 7^th EXAMINATION — WINTER -2019

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Subject Code: 2270002 Date:18/11/2019

Subject Name: Pharmaceutical Technology - I

Time: 10:30AM TO 01:30PM Total Marks: 80

Instructions:

1. Attempt any five questions.

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2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

1. (a) Write in details about containers used for aerosols. How will you evaluate pharmaceutical aerosols? 06
2. (b) Enlist the quality control tests for injectables. Explain rabbit test and LAL test. 05
3. (c) Define: Pharmaceutical Aerosols. Give a brief account of propellant and its selection. 05

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1. (a) What are the sources of contamination & methods of prevention in sterile dosage formulations? 06
2. (b) Draw well labeled diagram for aerosols packs. Explain different parts of valve assembly. 05
3. (c) Explain the mechanism of drug penetration through skin. Discuss factors affecting drug absorption through skin from semisolid dosage forms. 05

1. (a) Write a brief note on formulation of ophthalmic dosage form. Discuss ocular inserts for ophthalmic use. 06
2. (b) Write a short note on 1. Prefilled syringes 2. TPN 05

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3. (c) Classify different types of glass as per USP: Describe Water attack test for glass. 05

1. (a) Enumerate ideal characteristics of suppository bases. Describe methods of manufacturing suppositories in detail. 05
2. (b) Write brief note on: 1. Baby care products 2. Hygienic preparations 05
3. (c) Write a detailed note on storage and purity of W.F.I. 06

1. (a) Comment: Sedimentation rate of flocculated suspensions is faster than deflocculated suspensions. Differentiate flocculated and deflocculated suspension. 05

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2. (b) Write brief notes on 1. Tincture 2. Extracts 3. Infusion 05
3. (c) What are various instabilities of emulsions? Discuss them with their causes and precautions to avoid them 06

1. (a) Write brief notes on: 1. SOPs 2. Recovery and reprocessing 3. Personnel 05
2. (b) Write detailed note on formulation, preparation and evaluation of : 1. Sunscreen 2. Nail polish 05
3. (c) What are different types of validation? Write short note on validation of granulation stage in tablet manufacturing. 06

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1. (a) Write brief note on formulation, preparation & evaluation of shampoo and conditioners. 05
2. (b) Define Validation. Write a note on validation of steam sterilization. 05
3. (c) Write a note on semi solid bases. Enumerate their selection & ideal requirement 05

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