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Seat No.: Enrolment No.
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GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm — SEMESTER-VII EXAMINATION — WINTER -2019
Subject Code: 270006 Date: 28/11/2019
Subject Name: Pharmacology- II
Time: 10.30 AM to 01.30 PM Total Marks: 80
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) Classify immunosuppressive agents. Describe the mechanism of action, therapeutic use and adverse effect of Tacrolimus. 06
- (b) Explain synthesis, storage and release of thyroid hormones. 05
- (c) Describe the therapeutic uses and adverse effects of Glucocorticoids. 05
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- (a) Write in brief about mechanism of action, adverse effects and therapeutic uses of acyclovir. 06
- (b) Write short notes on estrogens and antiestrogens 05
- (c) Classify antiulcer agents? Write a note on proton pump Inhibitors. 05
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- (a) Explain mechanism of action of antimicrobial agents that interfere with cell wall synthesis with suitable illustrations. 06
- (b) Classify antineoplastic agents and explain mechanism of action of alkylating agents. 05
- (c) Give short note on expectorants and classify drugs used in asthma. 05
- (a) Write the anti-bacterial spectrum, mechanism of action and therapeutic uses of cephalosporins. 06
- (b) Describe the physiological actions of nitric oxide 05
- (c) Write a short note on oral contraceptives 05
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- (a) Discuss in detail about mechanism of action, adverse effects and therapeutic uses of rifampicin. 06
- (b) Classify antifungal drugs. Write in brief about amphotericin B. 05
- (c) Write short note on antiemetics 05
- (a) Explain the mechanism of action of insulin. Write a note on different insulin preparations and their indications. 06
- (b) Explain in detail biochemical mechanisms of resistance to antibiotics. 05
- (c) Write mechanism of action and therapeutic uses of ornidazole 05
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- (a) Write a short note on mechanism, side effects, therapeutic effects and antibacterial spectrum of streptomycin. 06
- (b) Classify antimalarial drugs. Write pharmacological actions of quinine. 05
- (c) Write a note on oxytocics. 05
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