Seat No.:
Subject Code: 2280002
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 8 EXAMINATION - WINTER -2019
Subject Name: Pharmaceutical Technology 1T
Time: 02:30 PM TO 05:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 | (a) | Write in details about matrix tablet and its evaluation. | 06 |
(b) | Give objectives of tablet coating. | 05 | |
(c) | Explain physics of tablet formation. | 05 | |
Q.2 | (a) | Explain in brief defects in tablet formation. | 06 |
(b) | Write advantages and disadvantages of tablets. | 05 | |
(c) | Discuss different film coating defects. | 05 | |
Q.3 | (a) | What is Pelletization? Discuss factors affecting pellet properties. | 06 |
(b) | Write a brief note on the size of capsules. | 05 | |
(c) | Discuss different granulation techniques for tablets. | 05 | |
Q.4 | (a) | Write a note on coacervation- Phase separation technique for microencapsulation. | 06 |
(b) | Write application of extrusion in Pharmacy. | 05 | |
(c) | Explain pharmaceutical application of supercritical fluids in extraction. | 05 | |
Q.5 | (a) | Write a note on influence of packaging components on dosage form stability. | 06 |
(b) | Discuss different methods for evaluation of packaging. | 05 | |
(c) | Explain tamper proof packaging. | 05 | |
Q.6 | (a) | Write on any two: 1) Binders 2) Disintigrant 3) Diluents. | 06 |
(b) | Write short note on techniques of SCF and one equipment for SCF processing. | 05 | |
(c) | Explain in brief pharmaceutical tablet compression tooling. | 05 | |
Q.7 | (a) | Define capsules and write quality control tests on hard gelatin capsules. | 06 |
(b) | Write a note on Melt Extrusion technology. | 05 | |
(c) | Discuss role of polyethylene oxide and eudragit in melt extrusion. | 05 |
Total Marks: 80
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Date: 16-11-2019
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