Download GTU B.Pharma 2019 Winter 8th Sem 2280016 Current Advances In Novel Drug Delivery Systems Question Paper

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Seat No.: Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

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B.PHARM - SEMESTER- 8 EXAMINATION — WINTER -2019
Subject Code: 2280016 Date: 27-11-2019
Subject Name: Current advances in Novel Drug Delivery Systems
Time: 02:30 PM TO 05:30 PM Total Marks: 80

Instructions:

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1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) What are the demerits of Nanoparticles? Explain its methods of preparation. 06
(b) What do you mean by Vesicular Drug Delivery System? Give its advantages, disadvantages and applications. 05

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(c) Differentiate between Liposomes and Niosomes. 05

Q.2 (a) Write a note on characterization of Niosomes. 06
(b) Enumerate different methods to prepare Micro-capsules and explain any one in detail. 05
(c) Explain drug loading concept in Vesicular Drug Delivery System. 05

Q.3 (a) What is Mucoadhesive film? Classify them and discuss characterization of same. 06

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(b) Explain Electro-osmosis method for Transdermal Drug Delivery System. 05
(c) Enlist the theories of Mucoadhesion and explain mechanism for Bioadhesion. 05

Q.4 (a) Enlist different approaches of In-situ Gel preparation. Explain enzyme sensitive In-situ Gel in detail. 06
(b) Differentiate between Diskettes and Strips. 05
(c) Differentiate between Iontophoresis and Sonophoresis. 05

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Q.5 (a) Explain any three out of the below mentioned terms, 06

1. Proliposomes
2. Dry granular Liposomes
3. Protransferosomes

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4. Lipopolyplexes
5. Ethosomes
6. Transferosomes

(b) Describe evaluation parameters of SEDDS. 05
(c) Explain drug loading concept in Vesicular Systems. 05

Q.6 (a) Explains different mechanisms of Sonophoresis. 06

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(b) Explain Drug selection criteria to formulate Transdermal patches. 05
(c) Write a short note on Minitablets. 05

Q.7 (a) Describe recent Innovations in Pelletization techniques. 06
(b) Write a short note on Phase Separation Coacervation method. 05
(c) Describes in detail applications of Hydrogels. 05

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