Download GTU B.Pharma 2019 Summer 3rd Sem 230005 Pathophysiology Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 3rd Sem 230005 Pathophysiology Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 3 EXAMINATION ? SUMMER -2019
Subject Code: 230005 Date: 07-06-2019
Subject Name: Pathophysiology
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a)
Enumerate the types of hypersensitivity reactions. Explain about pathogenesis of 06
B-cell mediated hypersensitivity reactions

(b)
Classify nutritional diseases. Write note on Vitamin B12 deficiency.
05

(c)
Write note on amyloidasis.
05



Q.2 (a)
Discuss pathologic basis of fatty liver.
06

(b)
What is calcification? Discuss types of calcifications with suitable examples.
05

(c)
Write a note on carbon monoxide poisoning.
05



Q.3 (a)
Discuss common diseases caused by environmental and occupational exposure. 06

(b)
Define healing. Discuss primary union of skin wounds.
05

(c)
Explain the mechanisms of rejection of allografts in hosts.
05



Q.4 (a)
Discuss basic mechanisms involved in inflammation.
06

(b)
Define immunity. Add a note on adaptive immunity.
05

(c)
Write a note on obesity.
05



Q.5 (a)
Define apoptosis. Write in detail about mechanism of apoptosis.
06

(b)
Write a note on biological effects of radiation.
05

(c)
Explain the terms:
05
i. Natural killer cell ii. T lymphocytes iii. MHC molecule
iv. Central tolerance v. Polyarteritis Nodosa



Q. 6 (a)
Explain the cellular and molecular mechanism of reversible and irreversible 06
injury due to hypoxia/ischemia .

(b)
Differentiate kwashiorkor and marasmus
05

(c)
Discuss pathogenesis of AIDS.
05



Q.7 (a)
Enlist various autoimmune diseases. Write a note on etiology and pathogenesis 06
of systemic lupus erythematosus (SLE).

(b)
Write in detail about components of extracellular matrix (ECM).
05

(c)
Describe in brief glycogen storage diseases
05
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