Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 3rd Sem BP302TP Physical Pharmaceutics I Previous Question Paper
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 3 EXAMINATION ? SUMMER -2019
Subject Code: BP302TP Date: 30-05-2019
Subject Name: Physical Pharmaceutics I
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Describe Raoult's law with its application.
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(b) Define following terms
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(i) Solution (ii) Solute (iii) Solvent (iv) Saturated solution (v) supersaturated
solution.
(c) Enumerate factors affecting solubility and discuss common ion effect in detail. 05
Q.2 (a) Discuss the factors affecting solubility of gas in liquids.
06
(b) What is polymorphism? Discuss it with suitable examples.
05
(c) Briefly explain (i) Glassy state and (ii) Liquid crystals.
05
Q.3 (a) Explain sublimation with suitable diagram.
06
(b) What is the significance of specific rotation in pharmacy?
05
(c) Write a note on Du Nouy Tensiometer.
05
Q.4 (a) Explin spreading coefficient.
06
(b) Give the range of HLB value of (i) Detergents (ii) wetting agents (iii) o/w 05
emulsifying agents (iv) Antifoaming agents (v) Solubilizing agents
(c) What is physisorption? Differentiate physisorption and chemisorptions.
05
Q.5 (a) Explain the significance of protein binding.
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(b) Write a short note on Clathrates.
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(c) Write a short note on ligands.
05
Q. 6 (a) Classify the complexes and explain chelates in detail.
06
(b) Explain Sorensen's pH scale.
05
(c) Write a note on pH determination.
05
Q.7 (a) Explain Henderson-Hasselbalch equation.
06
(b) What are the methods of adjusting tonicity? Discuss freezing point method in 05
detail.
(c) Explain the limitation of distribution law.
05
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