Download GTU B.Pharma 2019 Summer 4th Sem 240003 Pharmaceutical Chemistry Iv Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 4th Sem 240003 Pharmaceutical Chemistry Iv Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 4 EXAMINATION ? SUMMER -2019
Subject Code: 240003 Date: 15-05-2019
Subject Name: Pharmaceutical Chemistry - IV
Time: 10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Discuss with reaction mechanism Howarth synthesis of Naphthalene
06

(b) How does structure effect the basicity of amines?
05

(c) Note on Hofmann degradation of amides.
05



Q.2 (a) Note on (1) Biphenyls (2) Allens (3) Spirans.
06

(b) Explain nucleophilic addition reaction of carbonyl compounds.
05

(c) Explain Hybridization and resonance in benzene.
05



Q.3 (a) Discuss the preparation of carboxylic acid.
06

(b) Explain Aldol and Crossed aldol condensation.
05

(c) Give the methods of preparation of carbonyl compounds.
05



Q.4 (a) Explain stereoselective and stereospecific reactions.
06

(b) Define (1) Chirality (2) Optical activity (3) Enantionmer (4) Recemic mixture
05
(5) Geometric isomerism.

(c) What is R and S configuration? Explain it.
05



Q.5 (a) Give reaction mechanism of Reamer Tiemann reaction and Kolbe Schmitt
06
reaction.

(b) Give the general methods for the preparation of aromatic amines.
05

(c) Explain mechanism of (i) Cannizaro reaction (ii) Perkin condensation.
05



Q. 6 (a) Give the methods for preparation of Phenol
06

(b) Explain Friedel crafts reaction.
05

(c) Defines arenes. Give methods for preparation of arenes.
05



Q.7 (a) Define nanochemistry. Explain its application in pharmacy.
06

(b) Give the principle of microwave synthesis.
05

(c) How helps Green chemistry to decrease pollution?
05
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