GTU B.Pharm 2019 Summer Question Papers || Gujarat Technological University
Seat No.:
Subject Code: 240005
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 4 EXAMINATION - SUMMER -2019
Subject Name: Pharmacology - I
Time: 10:30 AM TO 01:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
| Q.1 | (a) Explain the following terms:
--- Content provided by FirstRanker.com --- | 06 |
| (b) Write a short note on local anesthetics. | 05 | |
| (c) Describe the pharmacological and physiological role of serotonin. | 05 | |
| Q.2 | (a) Explain Dose response relationship and its importance. | 06 |
| (b) Briefly explain various types of animal toxicity studies. | 05 | |
| (c) Classify sympathomimetic drugs. | 05 | |
| Q.3 | (a) Define biotransformation. Describe enzyme induction and enzyme inhibition with examples. | 06 |
| (b) Explain signal transduction mechanism of G-protein coupled receptors. | 05 | |
| (c) Explain in detail about anticholinesterase poisoning and its treatment. | 05 | |
| Q.4 | (a) Enumerate routes of drug administration. Give the merits and demerits of intravenous route of drug administration. | 05 |
| (b) Explain drug antagonism. Give difference between competitive and non-competitive antagonism with suitable examples | 05 | |
| (c) Write a short note on drugs acting on autonomic ganglia. | 06 | |
| Q.5 | (a) Describe in short on the following
| 05 |
| (b) Give difference between non depolarizing agents and depolarizing agents as neuromuscular blockers. | 05 | |
| (c) Explain plasma protein binding of drugs and its clinically significant implications with suitable examples. | 06 | |
| Q.6 | (a) Classify muscarinic and nicotinic receptors with subtypes and explain pharmacological action of Acetylcholine. | 05 |
| (b) Define drug and explain different sources of drugs | 05 | |
| (c) Write a short note on bioavailability | 06 | |
| Q.7 | (a) Write a short note on neurohumoral transmission. | 05 |
| (b) Explain drug tolerance and dependence. | 05 | |
| (c) Write a short note on phases of clinical trials. | 05 |
Date: 15-05-2019
Total Marks: 80
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