Download GTU B.Pharma 2019 Summer 6th Sem 2260002 Pharmaceutical Microbiology And Biotechnology Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2019 Summer 6th Sem 2260002 Pharmaceutical Microbiology And Biotechnology Ii Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER? 6 EXAMINATION ? SUMMER -2019
Subject Code: 2260002 Date: 10-05-2019
Subject Name: Pharmaceutical Microbiology & Biotechnology ? II
Time: 02:30 PM TO 05:30 PM
Total Marks: 80
Instructions:


1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify the mutagenic agents and Describe test for identification of mutagens.
06

(b) Write a note on protoplast fusion.
05

(c) Define gene cloning. Discuss gene cloning by Restriction endonuclease.
05



Q.2 (a) How do you carried out sterility test for Iodex, sulfacetamide eye drops,
06
Penicillin, Talcum powders and surgical dressings.

(b) Differentiate transformation and transduction.
05

(c) Write a note on Hybridoma Technique.
05



Q.3 (a) Explain Microbiological test of vitamin B12.
06

(b) Discuss the growth promotion test.
05

(c) Comments: (i)TAB is a simple monovalent vaccine.(ii) Sub culturing is
05
required in sterility testing of oily injections.



Q.4 (a) Discuss antigen antibody reactions.
06

(b) Write a note on ELISA and Widal Tests.
05

(c) Differentiate Humoral and Cellular immunity, Active and passive immunity.
05



Q.5 (a) Give examples of Polyvalent vaccine, Toxoid, Attenuated vaccine, viral
06
vaccine, killed vaccine and sera.

(b) Write a note on immunoglobulins.
05

(c) Write a note on streptokinase.
05



Q. 6 (a) Write a note on collection, processing and storage of whole human blood.
06

(b) Write a note on ideal requirements of plasma substitutes and Dextran.
05

(c) Give schematic diagram of production of penicillin V by fermentation.
05



Q.7 (a) Give the organisms required for production of Streptomycin, Tetracycline,
06
Citric acid, Vitamin B12, Riboflavin and alcohol.

(b) Define fermentation. Draw labeled diagram of typical fermentor and give role
05
of different parts of fermentor.

(c) Discuss control of different parameters during fermentation process.
05
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