GTU B.Pharm 2019 Summer Question Papers || Gujarat Technological University
Seat No.:
Subject Code: 270003
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER- 7 EXAMINATION - SUMMER -2019
Subject Name: Pharmaceutical Chemistry-IX (Medicinal Chemistry)
Time: 02:30 PM TO 05:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
- (a) What are sulfonamides? Write Mechanism of action and SAR of Sulfonamides. 06
- (b) Briefly explain SAR of Fluoroquinolones. 05
- (c) Write synthesis of Thiotepa and Chloramphenicol 05
- (a) Write Mechanism of action, uses, side effects and degradation of Penicillins. 06
- (b) Write detail SAR of Cephalosporins. 05
- (c) Write short notes on Aminoglycosides antibiotics. 05
- (a) Briefly explain SAR of Tetracyclines. 06
- (b) Write mechanism of action, chemistry and uses of Macrolide antibiotics. 05
- (c) Write synthesis of Isoniazid and Chloroquine. 05
- (a) What are antitubercular agents? Briefly explain first line antitubercular agents. 06
- (b) Write short notes on Antifungal agents. 05
- (c) Write synthesis of Albendazole and Metronidazole 05
- (a) Briefly explain Antiviral agents. 06
- (b) What are immunomodulators? Write detail notes on Immunosuppressive agents. 05
- (c) Write synthesis of Amantadine and Tamoxifen 05
- (a) What are antineoplastic agents? Write detail notes on Alkylating anticancer agents. 06
- (b) Write short notes on antimetabolite anticancer agents. 05
- (c) Explain antithyroid drugs. Write synthesis of Methimazole. 05
- (a) What is diabetes? Write detail notes on oral hypoglycemic agents. 06
- (b) Briefly explain nomenclature and stereochemistry of steroids. 05
- (c) Write detail SAR on Adrenocorticoids. 05
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Date: 13-05-2019
Total Marks: 80
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