Download GTU B.Pharma 2018 Winter 1st Sem 2210001 Unit Operation I Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 1st Sem 2210001 Unit Operation I Previous Question Paper

Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 1- EXAMINATION ?WINTER - 2018

Subject Code:2210001
Date: 01/01/2019
Subject Name: Unit Operation-I
Time:10:30 AM TO 01:30 PM
Total Marks: 80

Instructions:

1. Attempt any five questions.

2. Make Suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

Q.1 (a) Explain the mechanisms of size reduction.
06

(b) Give principle and construction of hammer mill.
05

(c) Discuss importance of correct speed in operation of ball mill and write
05
disadvantages of ball mill.



Q.2 (a) What is screening of powders? Write grades of powder in brief according to IP.
06

(b) Discuss principle, working, advantages and disadvantages of the sieve shaker
05
machine.

(c) Give major applications of size reduction of drug substances.
05



Q.3 (a) Write a short note on cyclone separator.
06

(b) Explain term mixing and give mechanisms of mixing in solids.
05

(c) Discuss the factors affecting mixing of solids.
05



Q.4 (a) Explain construction, advantages, disadvantages and applications of double
06
cone blender.

(b) Write a note on planetary mixer.
05

(c) Explain the term crystallization and give it's major applications.
05



Q.5 (a) Describe theory of crystallization in brief.
06

(b) Draw Mier's Solubility Curve and explain it in brief.
05

(c) Write a brief note on Krystal crystallizer.
05



Q. 6 (a) Give theory and types of extraction.
06

(b) Write in brief on super critical fluid extraction.
05

(c) Discuss elements of automatic process control systems in brief.
05



Q.7 (a) Enumerate various process variables and write measurement of any one of them 06
in automated process.

(b) Discuss the chemical hazards and its prevention in pharmaceutical industries.
05

(c) Discuss waste water management system in industries.
05
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