Download GTU B.Pharma 2018 Winter 3rd Sem BP301TP Pharmaceutical Organic Chemistry Ii Question Paper

Download GTU (Gujarat Technological University Ahmedabad) B.Pharma (Bachelor of Pharmacy) 2018 Winter 3rd Sem BP301TP Pharmaceutical Organic Chemistry Ii Previous Question Paper

Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM ? SEMESTER ? 3- EXAMINATION ?WINTER - 2018

Subject Code: BP301TP
Date: 30/11/2018
Subject Name: Pharmaceutical Organic Chemistry II
Time: 10:30 AM TO 01:30 PM
Total Marks: 80
Instructions:

1. Attempt any five questions.

2. Make Suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

Q.1 (a) How alcohols differ from phenol? Explain structure of benzene based on
06
chemical properties.

(b) Explain this term "Aqueous solution of phenol is more acidic than alcohol "
05

(c) Notes on
05
a) Aromatic amine is less basic than aliphatic amine and ammonia
b) Cyclopropane is more prone to undergo ring opening reaction than
cyclobutane.



Q.2 (a) Explain hydrogenation of oil with diagram. Discuss significance and principal
06
of acid value and saponification value.

(b) What is the proof for the presence of two fused rings in naphthalene? Explain
05
about Haworth synthesis.

(c) Notes on inductive group and its directing effect in monosubstituated benzene.
05



Q.3 (a) Write down sulphonation, Friedel-Crafts acylation, reduction and oxidation
06
reaction of naphthalene.

(b) Explain effect of substituents on acidity of phenol.
05

(c) Notes on structure and stability of benzene.
05



Q.4 (a) What are synthetic uses of aryl diazonium salts?
06

(b) Discuss Baeyer strain theory using concept of angle strain. Limitation of
05
Baeyer strain theory.

(c) Notes on a) Why is chair conformation of cyclohexane more stable than boat
05
Form
b) Theory of strainless rings.



Q.5 (a) Explant Haworth synthesis for anthracene. Explain chemical reaction involve in 06
anthracene.

(b) Write down structure and uses of DDT, BHC and Chloramine.
05

(c) Explain briefly about electrophilic substitution reaction of benzene.
05



Q. 6 (a) How will you convert phenol in to (a) Benzene (b) Phenyl acetate (c) Anisole
06
(d) Phenetole (e) Salicylaldehyde (f) P- Hydroxyazobenzene

(b) Explain effect of substituents on acidity of Aromatic acids.
05

(c) Write down structure and uses of phenol, cresol and resorcinol.
05



Q.7 (a) What is aromaticity? Write down characteristic in aromatic benzene. Write
06
down method of preparation of benzene.

(b) How can you prepare phenol by Dow and Cumene process?
05

(c) Write down reaction involve in Cyclopropane and cyclobutane.
05
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