Download GTU B.Pharma 2018 Winter 7th Sem 2270004 Pharmacology And Pharmacotherapeutics Iii Question Paper

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Seat No.: Enrolment No.

GUJARAT TECHNOLOGICAL UNIVERSITY

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B.PHARM - SEMESTER - 7- EXAMINATION -WINTER - 2018

Subject Code: 2270004 Date: 22/11/2018

Subject Name: Pharmacology and Pharmacotherapeutics — 111

Time: 10:30 AM TO 01:30 PM Total Marks: 80

Instructions:

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1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1

1. (a) Classify antimicrobial agents and give disadvantages of combined antimicrobial agents therapy. (06)

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2. (b) Explain the different mechanisms of resistance with examples. (05)
3. (c) Write a note on antifungals. (05)

Q.2

1. (a) Discuss the mechanism of (any five): (10)
   1. 1) Griseofulvin
   2. 2) Chloramphenicol

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   3. 3) Vancomycin
   4. 4) Oseltamivir
   5. 5) Clavulanic acid
   6. 6) Cotrimoxazole

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2. (b) What is DOTS? Write a short note on management of Tuberculosis. (06)

Q.3

1. (a) Classify cephalosporins. Explain their mechanism of action and adverse effects. (06)
2. (b) Explain in detail the pharmacology of Ciprofloxacin. (05)
3. (c) Discuss the pathophysiology and management of Enteric infection. (05)

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Q.4

1. (a) Discuss the pathophysiology and treatment of Prostate Cancer. (10)
2. (b) Describe the complications and management of Hodgkin’s Lymphoma. (06)
3. (c) Write a note on macrolides. (06)

Q.5

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1. (a) Give the principle use and adverse effects of (any four): (05)
   1. 1) Streptomycin
   2. 2) Zidovudine
   3. 3) Dapsone
   4. 4) Acyclovir
   5. 5) Tetracycline

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2. (b) Discuss the pathophysiology, prevention and management of Amoebiasis. (05)

Q.6

1. (a) Classify anticancer drugs highlighting their mechanism of action. (10)
2. (b) Discuss the pathophysiology, complications and management of Leptospirosis. (06)

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3. (c) Discuss the management of UTI. (06)

Q.7

1. (a) Comment: (05)
   1. 1) Gray baby syndrome is a common adverse effect of Chloramphenicol.
   2. 2) Adrenaline is used in penicillin induced Anaphylaxis.
   3. 3) Pyridoxine is used concomitantly with Isoniazid.

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2. (b) Write a note on anthelmentics. (05)
3. (c) Outline the life cycle of Malarial parasite. Discuss the use of “Co-artemether”. (05)

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