Download NTRUHS 1st Year MBBS 2023 December Biochemistry Paper I Question Paper

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Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

MBBS DEGREE EXAMINATION - DECEMBER, 2023

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FIRST M.B.B.S. EXAMINATION

BIOCHEMISTRY- PAPER-I (SET-B)

(Multiple Choice Questions)

Time: 20 Minutes Max Marks: 20

Note: Answer all questions.

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SECTION-I (MCQs - 20 MARKS) 1X2=20

1. The following amino acid can enter the citric acid cycle as oxaloacetate:

   1. Lysine
   2. Proline
   3. Aspartate (Correct answer marked)

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   4. Serine

2. Oxidative phosphorylation and electron transport chain are inhibited by the following compounds, except:

   1. Carbon monoxide
   2. Hydrogen cyanide

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   3. Oligomycin
   4. Pyrophosphate

3. The coenzyme:

   1. Increases the affinity of apoenzyme to substrate

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   2. Lowers the activation energy
   3. Accepts one of the products of the reaction
   4. Increases the number of active sites of the enzyme

4. Enzymes bind to substrate:

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   1. By covalent bonds
   2. By glycosidic bond
   3. At catalytic site only
   4. Peptide bond

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5. A vitamin not available from plant source:

   1. Vitamin B1
   2. Vitamin B12
   3. Vitamin B2
   4. Vitamin K

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6. Mac Ardle's syndrome is due to deficiency of:

   1. Pyruvate kinase
   2. Glycogen synthase
   3. Muscle glycogen phosphorylase

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   4. Debranching enzyme

7. Which of the following enzyme is inhibited in starvation?

   1. Alanine transferase
   2. Glucokinase

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   3. Pyruvate carboxylase

8. Which of the following enzyme catalyzes substrate-level phosphorylation?

   1. Hexokinase
   2. Phosphofructokinase

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   3. Glycogen phosphorylase
   4. Pyruvate kinase

9. The serum lipoprotein with the highest cholesterol content is:

   1. High-density lipoprotein

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   2. Low-density lipoprotein
   3. Very low-density lipoprotein
   4. Chylomicron

10. Which of the following is not included in calculating the calorie requirement of an individual?

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    1. BMR
    2. RQ
    3. SDA
    4. Nature of work

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11. Lysine is deficient in:

    1. Cereals (rice and wheat)
    2. Maize and corn
    3. Pulses (Bengal gram dal)
    4. Tapioca (Cassava)

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12. The structure of vitamin A contains:

    1. Naphthoquinone ring
    2. Chromane ring
    3. Beta-ionone ring

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    4. Thiazole ring

13. The following enzyme of heme biosynthesis is inhibited by lead:

    1. ALA dehydratase
    2. UBG I Synthase

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    3. ALA synthase
    4. Coproporphyrinogen oxidase

14. Which of the following processes makes use of free radicals?

    1. Cell adhesion

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    2. Phagocytosis
    3. Contact inhibition
    4. Pinocytosis

15. Hypercholesterolemia is seen in the following conditions except:

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    1. Diabetes mellitus
    2. Hyperthyroidism
    3. Nephrotic syndrome
    4. Obstructive jaundice

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16. The chain elongation of fatty acid takes place in:

    1. Mitochondria
    2. Microsomes
    3. Golgi complex.
    4. Peroxisome

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17. The following are the features of starvation except:

    1. Ketoacidosis
    2. Glycogenolysis
    3. Increase in BMR

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    4. Gluconeogenesis

18. Specific gravity of urine is increased in:

    1. Chronic glomerulonephritis
    2. Diabetes mellitus

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    3. Liver disease
    4. Intake of vegetables

19. Beta oxidation of fatty acid forms all the following except:

    1. NADH

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    2. Acetyl CoA
    3. Malonyl CoA
    4. FADH2

20. Congenital erythropoietic porphyria is caused due to deficiency of:

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    1. Coproporphyrinogen oxidase
    2. Uroporphyrinogen III cosynthase
    3. PBG deaminase
    4. Protoporphyrinogen oxidase

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