Download NTRUHS 1st Year MBBS 2023 January Biochemistry Paper I Question Paper

Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

MBBS DEGREE EXAMINATION - JANUARY, 2023

FIRST M.B.B.S. EXAMINATION

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BIOCHEMISTRY- PAPER-I (SET-B)

(Multiple Choice Questions)

Time: 20 Minutes Max Marks: 20

Note: Answer all questions.

SECTION-I (MCQs - 20 MARKS) 1X2=20

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1. Which of the following coenzyme is required for HMP pathway?
1. Pyridoxal phosphate
2. Biotin
3. Thiamine pyrophosphate
4. Flavin adenine dinucleotide

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2. Which of the following is not a high energy compound?
1. Creatine phosphate
2. Glucose 6 phosphate
3. Phosphoenol pyruvate
4. 1,3 bisphosphoglycerate

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3. Long term regulation of enzyme action is affected by:
1. Altering the activity of enzyme protein
2. Induction and repression of enzyme protein synthesis
3. Premature breakdown of enzyme protein
4. Partial denaturation of enzyme protein

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4. A constitutive enzyme is:
1. Activated by an inducer
2. Inhibited by a repressor
3. Always present in the cell in the same concentration
4. A constituent of the cell membrane

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5. Insulin favors:
1. Gluconeogenesis
2. Cholesterol Synthesis
3. Lipogenesis
4. Ketogenesis

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6. Deficiency of Folic acid leads to:
1. Pellagra
2. Night Blindness
3. Macrocytic Anemia
4. Microcytic Anemia

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7. Which of the following enzyme generated NADPH?
1. Pyruvate carboxylase
2. Pyruvate dehydrogenase
3. Glucose 6 phosphate dehydrogenase
4. Lactate dehydrogenase

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8. Which of the following cannot be converted back to glucose?
1. Acetyl CoA
2. Lactate
3. Alanine
4. Propionyl CoA

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9. The main apoprotein present in HDL is:
1. Apo A1
2. B-100
3. B-48
4. Apo E

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10. Which of the below mentioned compound has highest calorific value:
1. Glucose
2. Amino Acid
3. Palmitic acid
4. Ethanol

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11. Negative nitrogen balance is observed in:
1. Pregnancy
2. Growth period
3. Chronic fever
4. Convalescence

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12. Large dose of Vitamin K in neonate can cause:
1. Cyanosis
2. Jaundice
3. Skin Disorder
4. Porphyria

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13. Heme is converted to bilirubin in:
1. Mitochondria
2. Microsomes
3. Golgi Bodies
4. Plasma Membrane

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14. The organelle concerned with free radical scavenging is:
1. Lysosome
2. Golgi Bodies
3. Nucleolus
4. Peroxisomes

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15. Refsum's disease is due to accumulation of:
1. Sphingomyelin
2. Glucocerebroside
3. Phytanic Acid
4. Ganglioside

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16. The tissue that cannot use fatty acids as fuel is:
1. Liver
2. Brain
3. Skeletal Muscle
4. Cardiac muscle

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17. Which of the following is Phase 3 reaction of Detoxification:
1. Epoxidation
2. Glucuronidation
3. Deconjugation
4. Dealkylation

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18. The pathway which takes place in mitochondria is:
1. Glycolysis
2. HMP pathway
3. Ketogenesis
4. Cholesterol synthesis

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19. Steroid hormone is produced from:
1. Purine
2. Pyrimidine
3. Cholesterol
4. Stercobilinogen

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20. Renal plasma flow is measured by:
1. Creatinine Clearance
2. Specific gravity of urine
3. Para amino Hippurate clearance
4. Urine output

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