Download NTRUHS 1st Year MBBS 2023 January Biochemistry Paper I Question Paper

Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

MBBS DEGREE EXAMINATION - JANUARY, 2023

FIRST M.B.B.S. EXAMINATION

BIOCHEMISTRY- PAPER-I (SET-B)

(Multiple Choice Questions)

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Time: 20 Minutes Max Marks: 20

Note: Answer all questions.

SECTION-I (MCQs - 20 MARKS) 1X2=20

1. Which of the following coenzyme is required for HMP pathway?
   1. Pyridoxal phosphate
   2. Biotin

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   3. Thiamine pyrophosphate
   4. Flavin adenine dinucleotide
2. Which of the following is not a high energy compound?
   1. Creatine phosphate
   2. Glucose 6 phosphate

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   3. Phosphoenol pyruvate
   4. 1,3 bisphosphoglycerate
3. Long term regulation of enzyme action is affected by:
   1. Altering the activity of enzyme protein
   2. Induction and repression of enzyme protein synthesis

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   3. Premature breakdown of enzyme protein
   4. Partial denaturation of enzyme protein
4. A constitutive enzyme is:
   1. Activated by an inducer
   2. Inhibited by a repressor

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   3. Always present in the cell in the same concentration
   4. A constituent of the cell membrane
5. Insulin favors:
   1. Gluconeogenesis
   2. Cholesterol Synthesis

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   3. Lipogenesis
   4. Ketogenesis
6. Deficiency of Folic acid leads to:
   1. Pellagra
   2. Night Blindness

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   3. Macrocytic Anemia
   4. Microcytic Anemia
7. Which of the following enzyme generated NADPH?
   1. Pyruvate carboxylase
   2. Pyruvate dehydrogenase

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   3. Glucose 6 phosphate dehydrogenase
   4. Lactate dehydrogenase
8. Which of the following cannot be converted back to glucose?
   1. Acetyl CoA
   2. Lactate

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   3. Alanine
   4. Propionyl CoA
9. The main apoprotein present in HDL is:
   1. Apo A1
   2. B-100

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   3. B-48
   4. Apo E
10. Which of the below mentioned compound has highest calorific value:
    1. Glucose
    2. Amino Acid

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    3. Palmitic acid
    4. Ethanol
11. Negative nitrogen balance is observed in:
    1. Pregnancy
    2. Growth period

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    3. Chronic fever
    4. Convalescence
12. Large dose of Vitamin K in neonates can cause:
    1. Cyanosis
    2. Jaundice

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    3. Skin Disorder
    4. Porphyria
13. Heme is converted to bilirubin in:
    1. Mitochondria
    2. Microsomes

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    3. Golgi Bodies
    4. Plasma Membrane
14. The organelle concerned with free radical scavenging is:
    1. Lysosome
    2. Golgi Bodies

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    3. Nucleolus
    4. Peroxisomes
15. Refsum's disease is due to accumulation of:
    1. Sphingomyelin
    2. Glucocerebroside

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    3. Phytanic Acid
    4. Ganglioside
16. The tissue that cannot use fatty acids as fuel is:
    1. Liver
    2. Brain

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    3. Skeletal Muscle
    4. Cardiac muscle
17. Which of the following is Phase 3 reaction of Detoxification:
    1. Epoxidation
    2. Glucuronidation

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    3. Deconjugation
    4. Dealkylation
18. The pathway which takes place in mitochondria is:
    1. Glycolysis
    2. HMP pathway

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    3. Ketogenesis
    4. Cholesterol synthesis
19. Steroid hormone is produced from:
    1. Purine
    2. Pyrimidine

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    3. Cholesterol
    4. Stercobilinogen
20. Renal plasma flow is measured by:
    1. Creatinine Clearance
    2. Specific gravity of urine

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    3. Para amino Hippurate clearance
    4. Urine output

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