CBME
DR. YSR UNIVERSITY OF HEALTH SCIENCES:AP:VIJAYAWADA-520 008
MBBS DEGREE EXAMINATION – JANUARY, 2023
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FIRST M.B.B.S. EXAMINATION
BIOCHEMISTRY – PAPER-II (Set B)
(Multiple Choice Questions)
Time: 20 Minutes Max Marks: 20
Note: Answer all questions
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SECTION - I (MCQs- 20 MARKS) 1x20=20
1) In pheochromocytoma, there is excess synthesis of
a. Vanillyl mandelic acid
b. Polyamines
c. Hippuric acid
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d. Indole acetic acid
2) Acetylcholine can be synthesized from which amino acid:
a. Tyrosine
b. Serine
c. Threonine
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d. Tryptophan
3) Ammonia is trapped in the brain by:
a. Glutamine synthase reaction
b. Carbamoyl phosphate synthase 1
c. Citrate synthase
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d. Glutamate dehydrogenase
4) Tertiary structure of protein describes:
a. The sequence of amino acids
b. The location of disulfide bonds
c. Amino terminal end amino acid
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d. The nature of protein folding
5) Formation of dTMP requires
a. Coenzyme A
b. NADPH
c. Vitamin C
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d. Molybdenum
6) Secondary hyperuricemia is present in all the following conditions
a. Polycythemia
b. Cytotoxic drug therapy
c. Leukemia
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d. Hepatitis
7) Which of the below mentioned enzyme does not contain copper:
a. Cytochrome oxidase
b. Superoxide dismutase
c. Xanthine oxidase
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d. Tyrosinase
8) Zinc is constituent of all the following enzymes except:
a. Alkaline phosphatase
b. Amylase
c. Carbonic anhydrase
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9) Which of the enzyme listed below is heat stable?
a. Restriction endonuclease
b. Thermo thermophilus
c. Reverse transcriptase
d. Enterokinase
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10) The following are the vectors for gene therapy except:
a. Retrovirus
b. E. Coli
c. Adenovirus
d. Liposome
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11) Unusual nucleotide bases are found in significant quantity in:
a. Messenger RNA
b. Ribosomal RNA
c. Transfer RNA
d. snRNA
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12) Denaturation of DNA is accompanied by all the following changes except:
a. Hyperchromicity
b. Increase in viscosity
c. Unstacking of base
d. Double helix structure
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13) Administration of diuretics causes loss of potassium ions which can lead to:
a. Metabolic alkalosis
b. Metabolic acidosis
c. Respiratory acidosis
d. Respiratory alkalosis
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14) Hydroxylation occurs in which of the following amino acids in collagen:
a. Threonine
b. Alanine
c. Lysine
d. Tryptophan
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15) Which of the following is due to tumor suppressor mutation?
a. Retinoblastoma
b. Hyperthyroidism
c. Cystic Fibrosis
d. Sickle cell disease
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16) The uptake of iodine by thyroid gland is inhibited by:
a. Fluoride
b. Perchlorate
c. Bromide
d. Chloride
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17) The following is not an acute phase protein:
a. CRP
b. Ceruloplasmin
c. HDL
d. Haptoglobin
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18) Sodium potassium pump is inhibited by:
a. Aspirin
b. Digoxin
c. Methotrexate
d. Rifampicin
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19) Oncogenes are specific sequences in DNA:
a. That are tumor markers
b. When expressed produce cancer
c. That code for reverse transcriptase
d. Required for DNA replication
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20) Patients treated with carbonic anhydrase inhibitor can develop:
a. Metabolic acidosis
b. Respiratory acidosis
c. Respiratory alkalosis
d. Metabolic alkalosis
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