Q.P. CODE: M102A031
Dr NTR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008
MBBS DEGREE EXAMINATION - AUGUST, 2024
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FIRST M.B.B.S. EXAMINATION
BIOCHEMISTRY - PAPER-II (SET-B)
(Multiple Choice Questions)
Time: 20 Minutes
Max Marks: 20
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Note: Answer all questions.
SECTION-I (MCQs - 20 MARKS)
1X2=20
- Which of the following enzymes requires Adenosine Triphosphate (ATP) for its action?
- Argino Succinate lyase
- Argino Succinate synthetase
- Arginase
- Glutaminase
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- Which of the following contributes nitrogen atoms to both purine and pyrimidine rings?
- Aspartate
- Carbamoyl phosphate
- Carbon dioxide
- Glutamate
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- The greatest buffering capacity at physiological pH would be provided by a protein rich in which of the following amino acids?
- Serine
- Cysteine
- Alanine
- Histidine
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- Purely ketogenic amino acid is
- Leucine
- Threonine
- Isoleucine
- Tyrosine
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- RNA synthesis is different from DNA synthesis in the following ways, except:
- No efficient proofreading function during RNA synthesis
- Primer is not involved in RNA synthesis
- DNA synthesis occurs with 5'-3' polarity, whereas RNA synthesis occurs with 3'-5' polarity
- 'U' replaces 'T' as the complementary base for 'A' in RNA synthesis
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- The translation factor which helps in forming ternary tRNA methionine complex is:
- elF2C
- elF4A
- elF4B
- elF3
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- Nucleosomes are a fundamental unit of DNA organization. It consists of histones complexed to DNA. Histone proteins present in nucleosomes are rich in which of the following amino acids:
- Histidine and lysine
- Lysine and arginine
- Arginine and histidine
- Histidine and valine
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- Which out of the following is not a product of tyrosine metabolism:
- Melanin
- Melatonin
- Thyroxin
- Epinephrine
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- Which one of these inhibits adenylyl cyclase:
- ACTH
- ADH
- Angiotensin II
- Glucagon
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- Which is the major intracellular cation:
- Na+
- K+
- Ca2+
- Mg2+
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- Normal anion gap metabolic acidosis is caused by:
- Cholera
- Starvation
- Ethylene glycol poisoning
- Lactic acidosis
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- The major urinary buffer is:
- Bicarbonate
- Phosphate
- Protein
- Hemoglobin
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- Marker enzyme for Golgi complex is:
- Galactosyl transferase
- Catalase
- Glucose 6 phosphatase
- None
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- Which of the following is a negative phase reactant
- C Reactive protein
- Albumin
- Fibrinogen
- Ferritin
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- Plasmids contain a
- Circular single stranded DNA
- Linear single stranded DNA
- Circular double stranded DNA
- Linear double stranded DNA
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- Which of the following immunoglobulin crosses placenta
- IgG
- IgM
- IgE
- IgA
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- Which of the following activity is not seen in DNA polymerase I
- 5' - 3' polymerase
- 3'-5' polymerase
- 5'-3' exonuclease
- 3' - 5' exonuclease
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- Highly repetitive DNA is seen in
- Telomere
- Centromere
- Both
- None
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- Which enzyme defect is seen in Homocystinuria type I
- Methionine synthase
- Cystathionine beta synthase
- Cystathioninase
- None of the above
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- All are involved in iron metabolism except
- Hepcidin
- Transthyretin
- Ceruloplasmin
- Ferroprotein
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