Download NTRUHS 1st Year MBBS 2022 May Biochemistry Paper I Question Paper

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CBME

Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

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MBBS DEGREE EXAMINATION -MAY, 2022

FIRST M.B.B.S. EXAMINATION

BIOCHEMISTRY- PAPER-I (SET-C)

(Multiple Choice Questions)

Time: 20 Minutes Max Marks: 20

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Note: Answer all questions.

SECTION-I (MCQs - 20 MARKS) 1X2=20

1. Which enzymes contains copper
   1. Cytochrome P450
   2. Cytochrome oxidase
   3. Cytochrome b5

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   4. Coenzyme Q
2. Serum alkaline phosphatase is increasing in
   1. Hypothyroidism
   2. Myocardial infarction
   3. Carcinoma of prostrate

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   4. Bone diseases
3. Death due to cyanide poisoning is result of
   1. Cyanide blocking oxygen transport in blood
   2. Cyanide hemoglobin complex formation
   3. Cyanide inhibiting complex of respiratory chain

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   4. Cyanide inhibiting cytochrome oxidase
4. Acute pancreatitis may be diagnosed by estimating serum levels of the enzyme
   1. Acid phosphatase
   2. Alanine transaminase
   3. Amylase

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   4. Alkaline phosphatase
5. All the following coenzymes are involved in pyruvate dehydrogenase reaction except
   1. Flavine Adenine Dinucleotide
   2. Thiamine Pyrophosphate
   3. Biotin

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   4. Nicotinamide Adenine Dinucleotide
6. Which enzyme in glycolytic pathway is inhibited by fluoride ions
   1. Aldolase
   2. Enolase
   3. Hexokinase

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   4. Phospho fructokinase
7. Pyruvate is converted to acetyl CoA by
   1. Lactate dehydrogenase
   2. Pyruvate dehydrogenase
   3. Pyruvate carboxylase

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   4. Pyruvate kinase
8. The key enzyme of glycolysis is
   1. Phosphohexose isomerase
   2. Phosphofructokinase
   3. Glucose 6 phosphatase

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   4. Glycolaldehyde 3 phosphate dehydrogenase
9. Nyctalopia is due to deficiency of
   1. Vitamin K
   2. Vitamin A
   3. Vitamin E

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   4. Vitamin B12
10. If the product is more toxic than original compound, which of the following toxin is used
    1. Conjugation
    2. Biotransformation
    3. Detoxification

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    4. Bioactivation
11. Vitamin K is inhibited by
    1. Isoniazid (INH)
    2. Avidin
    3. Methotrexate

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    4. Dicoumarol
12. Which of the following enzymes are involved in detoxification
    1. Decarboxylases
    2. Cytochrome P450 enzymes
    3. Transaminases

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    4. Dehydrogenases
13. Which of the vitamins listed has no antioxidant property
    1. Vitamin E
    2. Vitamin A
    3. Vitamin C

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    4. Vitamin K
14. Which is the enzyme specially involved in ossification of bone
    1. Hexokinase
    2. ATPase
    3. Alkaline phosphatase

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    4. Acid phosphatase
15. Which disease is associated with conjugated hyper bilirubinemia
    1. Dubin Johnson syndrome
    2. Congenital spherocytosis
    3. Gilbert disease

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    4. Crigler Najjar syndrome
16. Which of the following diseases are not attributed to free radical injury
    1. Cataract
    2. Reperfusion injury
    3. Retrolental fibroplasia

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    4. Hypothyroidism
17. Ketone bodies in urine are identified by
    1. Heat and acetic acid
    2. Benedicts test
    3. Rothera's test

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    4. Benzidine test
18. Heme contains
    1. Sodium
    2. Magnesium
    3. Calcium

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    4. Iron
19. The pathway which taken place in the Mitochondria is
    1. Ketogenesis
    2. Glycolysis
    3. Cholesterol synthesis

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    4. HMP shunt pathway
20. Fatty liver may be prevented by the following except
    1. Lecithin
    2. Ethanol
    3. Choline

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    4. Erythrocytes

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