Download NTRUHS 1st Year MBBS 2022 May Biochemistry Paper I Question Paper

Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

MBBS DEGREE EXAMINATION –MAY, 2022

FIRST M.B.B.S. EXAMINATION

BIOCHEMISTRY- PAPER-I (SET-C)

(Multiple Choice Questions)

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Time: 20 Minutes

Max Marks: 20

SECTION-I (MCQs - 20 MARKS)

1X2=20

1. Which enzymes contains copper
   1. Cytochrome P450

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   2. Cytochrome oxidase
   3. Cytochrome b5
   4. Coenzyme Q
2. Serum alkaline phosphatase is increasing in
   1. Hypothyroidism

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   2. Myocardial infarction
   3. Carcinoma of prostrate
   4. Bone diseases
3. Death due to cyanide poisoning is result of
   1. Cyanide blocking oxygen transport in blood

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   2. Cyanide hemoglobin complex formation
   3. Cyanide inhibiting complex of respiratory chain
   4. Cyanide inhibiting cytochrome oxidase
4. Acute pancreatitis may be diagnosed by estimating serum levels of the enzyme
   1. Acid phosphatase

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   2. Alanine transaminase
   3. Amylase
   4. Alkaline phosphatase
5. All the following coenzymes are involved in pyruvate dehydrogenase reaction except
   1. Flavine Adenine Dinucleotide

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   2. Thiamine Pyrophosphate
   3. Biotin
   4. Nicotinamide Adenine Dinucleotide
6. Which enzyme in glycolytic pathway is inhibited by fluoride ions
   1. Aldolase

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   2. Enolase
   3. Hexokinase
   4. Phospho fructokinase
7. Pyruvate is converted to acetyl CoA by
   1. Lactate dehydrogenase

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   2. Pyruvate dehydrogenase
   3. Pyruvate carboxylase
   4. Pyruvate kinase
8. The key enzyme of glycolysis is
   1. Phosphohexose isomerase

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   2. Phosphofructokinase
   3. Glucose 6 phosphatase
   4. Glycolaldehyde 3 phosphate dehydrogenase
9. Nyctalopia is due to deficiency of
   1. Vitamin K

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   2. Vitamin A
   3. Vitamin E
   4. Vitamin B12
10. If the product is more toxic than original compound, which of the following toxin is used
    1. Conjugation

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    2. Biotransformation
    3. Detoxification
    4. Bioactivation
11. Vitamin K is inhibited by
    1. Isoniazid (INH)

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    2. Avidin
    3. Methotrexate
    4. Dicoumarol
12. Which of the following enzymes are involved in detoxification
    1. Decarboxylases

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    2. Cytochrome P450 enzymes
    3. Transaminases
    4. Dehydrogenases
13. Which of the vitamins listed has no antioxidant property
    1. Vitamin E

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    2. Vitamin A
    3. Vitamin C
    4. Vitamin K
14. Which is the enzyme specially involved in ossification of bone
    1. Hexokinase

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    2. ATPase
    3. Alkaline phosphatase
    4. Acid phosphatase
15. Which disease is associated with conjugated hyper bilirubinemia
    1. Dubin Johnson syndrome

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    2. Congenital spherocytosis
    3. Gilbert disease
    4. Crigler Najjar syndrome
16. Which of the following diseases are not attributed to free radical injury
    1. Cataract

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    2. Reperfusion injury
    3. Retrolental fibroplasia
    4. Hypothyroidism
17. Ketone bodies in urine are identified by
    1. Heat and acetic acid

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    2. Benedicts test
    3. Rothera's test
    4. Benzidine test
18. Heme contains
    1. Sodium

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    2. Magnesium
    3. Calcium
    4. Iron
19. The pathway which taken place in the Mitochondria is
    1. Ketogenesis

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    2. Glycolysis
    3. Cholesterol synthesis
    4. HMP shunt pathway
20. Fatty liver may be prevented by the following except
    1. Lecithin

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    2. Ethanol
    3. Choline
    4. Erythrocytes

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