Q.P. CODE: M102A030
Dr NTR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008
MBBS DEGREE EXAMINATION - OCTOBER, 2024
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FIRST M.B.B.S. EXAMINATION
BIOCHEMISTRY- PAPER-I (SET-B)
(Multiple Choice Questions)
Time: 20 Minutes
Note: Answer all questions.
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Max Marks: 20
SECTION-I (MCQs - 20 MARKS) 1X2=20
1) Cori's cycle transfers
a) Glucose from muscles to liver
b) Lactate from muscles to liver
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c) Lactate from the liver to muscles
d) Pyruvate from the liver to muscles
2) Gluconeogenesis is decreased by
a) Glucagon
b) Epinephrine
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c) Glucocorticoids
d) Insulin
3) On boiling Benedict's solution is not reduced by
a) Fructose
b) Lactose
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c) Maltose
d) Sucrose
4) Two sugars which differ from one another only in configuration around a single carbon atom are termed
a) Epimers
b) Anomers
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c) Optical isomers
d) Stereoisomers
5) Among the following, the most sensitive indicator of glomerular function is
a) Serum Urea
b) Serum Creatinine
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c) Urea Clearance
d) Creatinine Clearance
6) Which of the following metabolite integrates glucose and fatty acid metabolism?
a) Acetyl CoA
b) Pyruvate
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c) Citrate
d) Lactate
7) Anaemia can occur due to the deficiency of all of the following except:
a) Thiamine
b) Pyridoxine
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c) Folic acid
d) Cyanocobalamin
8) Catalytic activity of salivary amylase requires the presence of
a) Chloride ions
b) Bromide ions
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c) lodide ions
d) All of these
9) HMG CoA is formed in the metabolism of
a) Cholesterol, ketones and Leucine
b) Cholesterol, fatty acid and Leucine
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c) Lysine, Leucine and Isoleucine
d) Ketones, Leucine and Lysine
10) All the following statements correctly describe ketone bodies except:
a) They may result from starvation
b) They are present at high levels in uncontrolled diabetes
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c) They include - OH B-butyrate and acetone
d) They are utilized by the liver during starvation
11) Phrynoderma is a deficiency of
a) Essential fatty acids
b) Proteins
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c) Amino acids
d) None of these
12) Gaucher's disease is due to a deficiency of the enzyme
a) Sphingomyelinase
b) Glucocerebrosidase
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c) Galactocerebrosidase
d) β-Galactosidase
13) Serum lactate dehydrogenase rises in
a) Viral hepatitis
b) Myocardial infarction
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c) Carcinomatosis
d) All of these
14) Both folic acid and vitamin B12 are required in
a) Deamination of serine
b) Deamination of threonine
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c) Conversion of pyridoxal phosphate to pyridoxamine phosphate
d) Methylation of homocysteine to methionine
15) The vitamin required for the formation of hydroxyproline during collagen synthesis is
a) Vitamin C
b) Vitamin A
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c) Vitamin D
d) Vitamin E
16) The most potent Vitamin D metabolite is
a) 25-hydroxycholecalciferol
b) 1,25-Dihydroxycholecalciferol
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c) 24, 25-Dihydroxycholecalciferol
d) 7-Dehydrocholesterol
17) An example of feedback inhibition is
a) Allosteric inhibition of hexokinase by glucose-6-phosphate
b) Cyanide action on cytochrome
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c) Sulpha drug on folic acid synthesizer bacteria
d) Reaction between succinic dehydrogenase and succinic acid
18) 'Clearing factor' is
a) Lipoprotein lipase
b) Crotonase
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c) 7-dehydro cholesterol
d) B-sitosterol
19) Acetyl CoA carboxylase is activated by
a) Citrate
b) Insulin
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c) Both A & B
d) None of these
20) Glucose-6-phosphate dehydrogenase is induced by
a) 6-Phosphogluconolactone
b) Glucose-6-phosphate
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c) Ribose-5-phosphate
d) Insulin
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