Download NTRUHS 2nd Year MBBS 2022 January Pharmacology Paper II Theory Question Paper

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CBME

Dr YSR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA- 520008

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MBBS DEGREE EXAMINATION - JANUARY, 2024

SECOND M.B.B.S. EXAMINATION

PHARMACOLOGY PAPER-II

(Multiple Choice Questions) (SET-C)

Time: 20 Minutes Max Marks: 20

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Note: Answer all questions.

SECTION-I (MCQs - 20 MARKS) 1X2=20

1. Which of the following antibiotics is given orally for the treatment of pseudomembranous colitis caused by Clostridium difficile?
   1. Vancomycin.
   2. Ampicillin
   3. Doxycycline

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   4. Clindamycin
2. Which of the following antibiotic acts by inhibiting protein synthesis?
   1. Cefazolin
   2. Methicillin
   3. Doxycycline

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   4. Ciprofloxacin
3. Which of the following drugs is combined with imipenem to increase its half-life?
   1. Sulbactam
   2. Cilastatin
   3. Avibactam

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   4. Pravastatin
4. Which among the following antibiotic is not an inhibitor of cell wall synthesis?
   1. Netilmicin
   2. Fosfomycin
   3. Bacitracin

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   4. Cycloserine
5. Cotrimoxazole contains sulfamethoxazole to trimethoprim in the ratio of
   1. 4:1
   2. 5:1
   3. 1:4

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   4. 1:5
6. The antibiotic of choice for surgical prophylaxis is
   1. Cefuroxime axetil
   2. Cefixime
   3. Cefazolin

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   4. Oritavancin
7. Mechanism of action of Ketoconazole
   1. Forming pores in fungal cell membrane
   2. Blocking glucan synthase
   3. Interfering with fungal ergosterol synthesis

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   4. Inhibiting epoxidation of squalene
8. Which among the following beta lactam antibiotics does not show cross allergenicity in patients allergic to penicillin
   1. Aztreonam
   2. Meropenem
   3. Imipenem

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   4. Methicillin
9. Which among the following drugs can be used for the treatment of a 26 year old woman with infertility and hyperprolactinemia?
   1. Levodopa
   2. Bromocriptine
   3. Methylergometrine

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   4. Misoprostol
10. Filgrastim is indicated for the treatment of
    1. Anemia
    2. Neutropenia
    3. Polycythemia

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    4. Eosinophilia
11. Which among the following drugs is used for the management of acute symptoms associated with hyperthyroidism such as tachycardia and palpitations
    1. Carbimazole
    2. Lugol's iodine
    3. Propranolol

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    4. Methimazole
12. All of the following statements are true about heparin except
    1. Contraindicated in pregnancy
    2. Protamine is the antidote for overdose
    3. Alopecia is an adverse effect

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    4. Intramuscular route is contraindicated
13. Tamoxifen is a
    1. Selective progesterone receptor modulator
    2. Selective estrogen receptor modulator
    3. Selective androgen receptor modulator

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    4. Selective glucocorticoid receptor modulator
14. Which among the following antidiabetic drugs can cause megaloblastic anemia due to vitamin B12 deficiency
    1. Glibenclamide
    2. Metformin
    3. Acarbose

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    4. Rosiglitazone
15. The drug useful in early first trimester abortion is
    1. Clomiphene citrate
    2. Leuprolide
    3. Oxytocin

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    4. Mifepristone
16. Which among the following conditions is a contraindication for use of glucocorticoids
    1. Renal transplant recipients
    2. Inflammatory bowel disease
    3. Acute uveitis

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    4. Varicella infection
17. Which among the given anticancer drugs is not an alkylating agent
    1. Lomustine
    2. Busulfan
    3. Fludarabine

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    4. Carmustine
18. Which of the following statements is true about misoprostol
    1. It is a methyl analogue of PGF2
    2. It is teratogenic in humans
    3. It requires single daily dosing for NSAID induced peptic ulcer

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    4. It has both acid inhibitory and mucosal protective properties
19. Which among the following chelating agents is known popularly as "British anti-lewisite"
    1. Succimer
    2. Unithiol
    3. Edette calcium disodium

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    4. Dimercaprol
20. Sucralfate is a salt of
    1. Sucrose complexed to sulphated aluminium sulphate
    2. Sucrose complexed to sulphated aluminium phosphate
    3. Sucrose complexed to sulphated aluminium hydroxide

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    4. Sucrose complexed to sulphated aluminium carbonate

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