Download NTRUHS 2nd Year MBBS 2025 January Pharmacology Paper II MCQs Question Paper

Dr NTR UNIVERSITY OF HEALTH SCIENCES : VIJAYAWADA - 8

MBBS DEGREE EXAMINATION - JANUARY,2025

SECOND M.B.B.S. EXAMINATION

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PHARMACOLOGY PAPER-II (SET-C)

(Multiple Choice Questions)

Time: 20 Minutes

Max Marks: 20

SECTION-I (MCQs - 20 MARKS)

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1X2=20

1. Neutropenia is an adverse effect of
   1. Methicillin
   2. Ampicillin
   3. Oxacillin
   4. Nafcillin

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2. Which of the following drug is a beta lactamase inhibitor
   1. Clavulanic acid
   2. Cilastatin
   3. Nicotinic acid
   4. Cerivastatin

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3. Vancomycin inhibits cell wall synthesis by inhibiting
   1. Enolpyruvate transferase
   2. Transpeptidase
   3. Transglucosylase
   4. Topoisomerase

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4. Which among the following antibiotics is not bactericidal
   1. Cefixime
   2. Colistin
   3. Linezolid
   4. Gentamicin

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5. Which of the following drug is used as an alternate to rifampicin for the treatment of tuberculosis in HIV/AIDS patients who are on protease inhibitors
   1. Rifapentine
   2. Clarithromycin
   3. Rifaximin
   4. Rifabutin

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6. The drug of choice for primary and secondary syphilis is
   1. Benzathine penicillin G
   2. Penicillin V
   3. Azithromycin
   4. Ampicillin

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7. Which of the following statements is not true about bedaquiline:
   1. Inhibits ADP synthase
   2. The mean terminal half-life is 5.5 months
   3. Contains FDA's black box warning.
   4. It is highly plasma protein bound (>99%)

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8. Which of the following statements is not true regarding daptomycin
   1. It is a lipopeptide antibiotic?
   2. It is effective against MRSA causing skin and soft tissue infections
   3. It is effective in the treatment of pneumonia caused by VRSA
   4. It is bactericidal

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9. Octreotide is used in all of the following conditions except
   1. Acromegaly
   2. Pituitary hypogonadism
   3. Secretory diarrhoea
   4. Bleeding oesophageal varices

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10. What factor is multiplied to body weight and hemoglobin deficit in the formula for calculating total iron requirement for parenteral iron therapy
    1. 6.3
    2. 3.3
    3. 4.3
    4. 5.3

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11. Hyperthyroidism induced due to iodide use is called as _______
    1. Wolff-Chaikoff effect
    2. Pendred syndrome
    3. Allan-Herndon-Dudley syndrome
    4. Jod-Basedow Phenomenon

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12. Vitamin K acts as a cofactor for _______ of clotting factors 2,7,9 and 10
    1. Deamination
    2. Carboxylation
    3. Oxidation
    4. Hydroxylation

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13. Oral contraceptive pills have beneficial effects in all of the following conditions except
    1. Ovarian cysts
    2. Endometrial cancer
    3. Thrombophlebitis
    4. Benign breast disease

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14. Which among the following preparations of insulin is not rapid and short acting
    1. Glargine
    2. Lispro
    3. Aspart
    4. Glulisine

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15. Which among the following drugs is not a SERM (Selective Estrogen Receptor Modulator)
    1. Tamoxifen
    2. Nalmefene
    3. Raloxifene
    4. Bazedoxifene

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16. Which of the following glucocorticoids is available as a topical preparation for the treatment of skin disorders
    1. Cortisone
    2. Triamcinolone
    3. Prednisone
    4. Paramethasone

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17. Leucovorin is used to decrease the toxicity due to
    1. Cyclophosphamide
    2. Cisplatin
    3. Methotrexate
    4. 5- Fluorouracil

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18. Which among the following antibiotics is not used for the treatment of helicobacter pylori induced peptic ulcer
    1. Clarithromycin
    2. Amoxicillin
    3. Ciprofloxacin
    4. Metronidazole

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19. Which among the following drugs is used orally for the management of transfusion related iron overload in patient with thalassemia
    1. Deferoxamine
    2. Succimer
    3. N-acetyl cysteine
    4. Deferiprone

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20. The antiemetic which acts by blocking the neurokinin1 (NK1) receptors in the central nervous system
    1. Aprepitant
    2. Ondansetron
    3. Doxylamine
    4. Metoclopramide

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