Download NTRUHS 2nd Year MBBS 2022 December Pharmacology Paper I MCQs Question Paper

Dr. NTR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA - 520 008
MBBS DEGREE EXAMINATION - DECEMBER, 2022
SECOND M.B.B.S. EXAMINATION

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PHARMACOLOGY - PAPER-I (SET-A)
(Multiple Choice Questions)
Time: 20 Minutes
Note: Answer all questions.
Max Marks: 20

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SECTION-I (MCQs - 20 MARKS)
1X2=20
1) Alkalinization of urine hastens the excretion of
a. Weakly basic drugs
b. Weakly acidic drugs

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c. Strong electrolytes
d. Nonpolar drugs
2) Which of the following constitutes 'drug abuse'
a. Physician prescribe use of penicillin G for the cure of viral fever
b. Self administration of aspirin to relieve headache

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c. Repeated self administration of morphine to derive euphoria
d. All of the same
3) If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting
a. Potentiation
b. Synergism

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c. Cross tolerance
d. Antagonism
4) Which of the following is always true
a. A more potent drug is more efficacious
b. A more potent drug is safer

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c. A more potent drug is clinically superior
d. A more potent drug can produce the same response at lower doses
5) Down regulation of receptors can occur as a consequence of:
a. Continuous use of agonists
b. Continuous use of antagonists

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c. Chronic use of CNS depressants
d. Denervation
6) Which of the following organs is innervated only by parasympathetic nerves
a. Iris muscles
b. Ciliary muscle

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c. Sweat glands
d. Splenic capsule
7) Pyridostigmine differs from neostigmine in that
a. It is more potent orally
b. It is longer acting

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c. It produces less muscarinic side effects
d. It does not have any direct action on NM receptors
8) The following mydriatic does not produce cycloplegia
a. Phenylephrine
b. Tropicamide

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c. Cyclopentolate
d. Homatropine
9) Which of the following is a selective alpha 1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure
a. Terazosin
b. Doxazosin

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c. Trimazosin
d. Tamsulosin
10) Allopurinol is indicated in the following category of chronic gout patients
a. Over producers of uric acid
b. Under excretor of uric acid

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c. Those with tophi and /or renal urate stones
d. All of the above
11) For a patient of peptic ulcer, the safest nonopioid analgesic is
a. Celecoxib
b. Diclofenac sodium

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c. Paracetamol
d. Ibuprofen
12) The following general anaesthetic has poor muscle relaxant action
a. Ether
b. Nitrous oxide

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c. Halothane
d. Isoflurane
13) Select the drug that has been found to reduce alcohol craving and chances of resume heavy drinking by alcoholics after they have undergone a detoxification programme
a. Chlordiazepoxide
b. Chlorpromazine

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c. Methadone
d. Naltrexone
14) Select the correct statement about benzodiazepines (BZDs)
a. All BZDs facilitate GABA mediated Cl influx into neurons
b. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant actions

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c. The BZD receptor is homogeneous at all neuronal sites
d. The muscle relaxant actions of BZDs is not blocked by flumazenil
15) The following drug displaces plasma protein bound phenytoin as well as decreases its metabolism
a. Carbamazepine
b. Sodium valproate

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c. Cimetidine
d. Chloramphenicol
16) Indications of desmopressin include the following except
a. Neurogenic diabetes insipidus
b. Nephrogenic diabetes insipidus

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c. Bedwetting in children
d. Bleeding due to haemophilia
17) Losartan differs from enalapril in the following respect
a. It does not potentiate bradykinin
b. It depresses cardiovascular reflexes

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c. It impairs carbohydrate tolerance
d. It does not have fetopathic potential
18) Which of the following drug is a potassium channel opener
a. Nicorandil
b. Hydralazine

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c. Gilbenclamide
d. Amiloride
19) Thiazide diuretics are the preferred first anti-hypertensives for the following category of patients
a. Young hypertensives
b. Physically and sexually active male hypertensives

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c. Elderly obese hypertensives
d. Diabetic hypertensives
20) The following antianginal drug is most likely to produce tachycardia as a side effect
a. Amlodipine
b. Nifedipine

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c. Dilitiazem
d. Verapamil
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