Download OU B.Pharma 2-1 Year 2013 7207 Pharmaceutical Organic Chemistry I Question Paper

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Code No. 7207

FACULTY OF PHARMACY

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B. Pharmacy II - Year I - Semester (Main) Examination, November 2013

Subject : Pharmaceutical Organic Chemistry - I

Time : 3 hours Max. Marks : 70

Note: Answer all questions. All questions carry equal marks.

1. a) i) Define and give the significances of Hydrogen bonding. 5
   

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   ii) Explain Isomerism with examples. 6
   iii) Define with example dipole moment. 3
   OR
   b) i) Give a note on polarity of molecules. 5
   ii) Describe the progress of a reaction with energy diagram. 6
   

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   iii) Write the significance of resonance effect. 3
2. a) i) Write any four methods of synthesis of alkanes. 7
   ii) Give the mechanism of free radical reactions. 7
   OR
   b) i) Explain the stability of cycloalkanes by different theories. 10
   

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   ii) Write the Anti Markonikov’s addition. 4
3. a) i) How will you distinguish between primary, secondary and tertiary alcohols. 8
   ii) Write any four methods of preparation of alkyl halides. 6
   OR
   b) i) Explain the elimination reaction with mechanism. 7
   

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   ii) Give different methods of synthesis of ethers. 7
4. a) Give any four methods for the synthesis of carboxylic acids. 8
   b) Write the synthetic applications of malonic ester. 6
   OR
   b) i) Give any four methods for synthesis of ketones. 8
   

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   ii) Write the synthetic applications of aceto-acetic ester. 6
5. a) i) How do you differentiate between primary, secondary and tertiary amines with chemical reactions? 8
   ii) Write the applications of Aryl diazonium salt. 6
   OR
   b) i) Discuss any four methods for synthesis of secondary aromatic amines. 8
   

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   ii) Give any three chemical reactions of aryl diazonium salt. 6

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