B. Pharmacy II-Year I-Semester (Supplementary) Examination, March 2014
Time : 3 Hours
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Code No. 7207/ S
FACULTY OF PHARMACY
Subject : Pharmaceutical Organic Chemistry - I
Note: Answer All questions. All questions carry equal marks.
-  - Explain the energy diagrams of reactants and products.
- Write about covalent bond and resonances.
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- Inductive effect
- Hybrid orbital
- Dipole movement
- Hydrogen bonding
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-  - Write the reaction and mechanism of following reactions.
- Catalytic reduction
- Markonikovs addition
- Halogenation of alkanes
- Allyllic substitution
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- Explain stability of conjugated alkadienes.
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-  -  - Give any three methods of preparation of alcohols.
- Explain in detail of SN1 reaction with mechanism.
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 OR -  - Give a note on Sayetzeff's rule and Walden inversion.
- Write different methods for synthesis of ethers.
 
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-  -  - Write any three methods for synthesis of aldehydes.
- Give the synthetic applications of malomic ester.
 
 OR --- Content provided by FirstRanker.com --- -  - Explain relative acidity of different carboxylic acids.
- Write synthesis of following:
- Esters
- Amides
- Acid halides
- Anhydrides
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-  -  - How to separate a mixture of amines by different methods.
- Give any three methods for synthesis of nitro alkanes.
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 OR -  - Write any three methods for synthesis of any diazonium salt.
- Give a note on basicity of amines by taking examples.
 
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Max. Marks: 70
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