Download OU B.Pharma 2-1 Year 2010 4410 Pharmaceutical Microbiology Question Paper

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Code No.: 4410

FACULTY OF PHARMACY

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B. Pharm. II Year I Semester (Main) Examination, Nov./Dec. 2010

PHARMACEUTICAL MICROBIOLOGY

Time : 3 Hours] [Max. Marks : 70

Note : Answer all questions. All questions carry equal marks.

1. a) i) Define the following : 6
   1. Miasma theory

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   2. Koch's Postulates
   3. Germ theory of diseases
   4. Abiogenesis
   Describe the different methods of Nutrition and cultivation of Micro organisms. 8

   OR

   b) i) Describe the organisms of pharmaceutical importance. 6 What is pure culture ? Explain the methods of obtaining pure culture and its preservation. 8

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2. a) i) Write the different types of identification of bacteria and explain IMViC tests. 8 ii) Explain in detail about the cultivation of anaerobic bacteria. 6

   OR

   b) i) Describe the Genetic organization, mutation and mutagens of Microbial Copulation. 9 ii) Explain the repair mechanism for chemical autogenesis. 6
3. a) i) Write about the different groups of disinfectants. 8 ii) Explain Rideal-Walker coefficient test. 6

   OR

   b) i) Classify sterilization. Explain Moist Heat sterilization. 8 h) What are sterilization indicators ? Explain the types of sterilization indicators. 6
4. a) i) Classify immunity. Explain Humoral and cell mediated immunity. ii) Define the following : 4
   1. Vaccine

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   2. Toxoid
   3. Antiserum
   4. Antitoxin

   OR

   b) i) Define hypersensitivity. Detail the types of hypersensitivity reactions. ii) Explain the various types of antibodies. 6

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5. a) i) Write about the general modes of transmission of diseases. Write the causative organism, mode of transmission, symptoms of the following diseases. 8
   1. Tuberculosis
   2. Infective Hepatitis
   ii) Write a detailed account on the pharmaceutical importance of E.coli and Saccharomyces species. 6

   OR

   b) i) Explain the various process of making potable-water. Write the microbial tests for potable water. 7 Write the methods of pasteurization of milk. Write the qualitative tests and grading of milk. 7

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