Download OU B.Pharma 2-1 Year 2016 4038 Pharmaceutical Oranic Chemistry I Question Paper

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Code No. 4038

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FACULTY

B. Pharmacy 2/4 I- Semester (Main) Examination, October 2016

Subject: Pharmaceutical Organic Chemistry -1

Time: 3 Hrs Max. Marks: 70

Note: Answer all questions. All questions carry equal marks.

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1. 1. Explain the energy diagrams of reactants and products during the course of reaction.
   2. Write a note on following:
      1. Hybridization
      2. Melting point
      3. Boiling point

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   OR

   1. Add a note on polarity of molecules.
   2. Define the terms with examples
      1. Inductive effect
      2. Cis trans isomerism
      3. Resonance

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2. 1. Discuss the free radical mechanism for the chlorination of methane.
   2. Write any four methods of preparation of alkanes.

   OR

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   1. Discuss the importance of Bayer’s strain theory.
   2. Explain the reactions of alkenes.
3. 1. How do you prepare ethers by Williamson's synthesis?
   2. Write a note on Saytzeff's rule.

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   OR

   1. Discuss about mechanism of nucleophilic substitution reactions.
   2. Write any two methods for synthesis of alcohols.
4. 1. Write the general reactions of carbonyl compounds.

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   2. Write any two methods of preparation of aldehydes.

   OR

   1. Discuss the reactivity and applications of malonic acid ester.
   2. Write any two methods of synthesis of carboxylic acids.

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5. 1. Write any two methods for synthesis of nitroalkanes.
   2. Write a note on aryldiazonium salts.

   OR

   1. Write a note on basicity of amines.
   2. How do you differentiate between primary, secondary and tertiary amines with chemical reactions?

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