Download OU B.Pharma 2-1 Year 2010 7010 Pharmaceutical Microbiology Question Paper

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Code No.: 7010

FACULTY OF TECHNOLOGY

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B. Pharmacy — II Year (I Semester) (Suppl.) Examination, June 2010

PHARMACEUTICAL MICROBIOLOGY

Time: 3 Hours] [Max. Marks: 70

Note : Answer all questions. All questions carry equal marks.

1. a) i) Explain the principle and application of fluorescence microscopy. 10
   

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   ii) Define and classify microbes with suitable examples. 4
   OR
   b) i) Describe the different techniques used for the isolation of micro-organisms in pure culture. 7
   ii) Explain about the different methods of bacterial cell count. 7
2. a) i) Describe the different types of mutations and how they affect the genetic code. 7
   

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   i) Explain the mode of action of UV light and nitrous acid. 7
   OR
   b) i) Discuss the morphology and reproduction in molds. 8
   i) What are point and 'frame shift' mutations ? Explain how modifications are different from mutations. 6
3. a) i) Explain the mode of action and practical application of the following : 8
   

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   A) Alkylating agents B) Heavy metals
   ii) Write about sterilization by filtration. 6
   OR
   b) i) Classify sterilization methods. What are non-thermal methods of sterilization ? 10
   ii) Write a note on sterilization by radiation. 4

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4. a) i) Describe various types of immunity with suitable examples. 10
   ii) Write a note on phagocytosis. 4
   OR
   b) i) Explain the antigen-antibody reactions. 10
   ii) Write a note on immunoglobulins. 4

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5. a) i) Write a note on presumptive test and confirmed test in identification of coliform bacteria. 10
   ii) Write the mode of transmission, diagnosis and treatment of the following diseases: 10
   i) Influenza ii) Filariasis
   OR
   b) i) Describe the systematic study of streptomyces species. 10
   

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   ii) Explain the principle, procedure and applications of pasteurization. 10

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