Download OU B.Pharma 3-1 Year 2017 4227 Pharmacoloy I Question Paper

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Code No. 4227

FACULTY

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B. Pharmacy 3/4 | Semester (Suppl.) Examination, May 2017

Subject : Pharmacology

Time : 3 Hrs Max. Marks: 70

Note: Answer all questions. All questions carry equal marks.

1. (a) What are different routes of drug administration? Compare the merits and demerits of oral and parenteral routes of administration. (8)
   

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   (b) Define the following: (6)
   1. (i) Therapeutic Index
   2. (ii) Biological Half life
   3. (iii) Synergism
   OR
   (c) Define and classify the receptors. Explain in detail about protein coupled receptors. (2+3+5)
   

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   (d) Write short notes on LD50 and ED50. (4)
2. (a) Explain the pharmacological effects and therapeutic uses of : (14)
   1. (i) Physostigmine
   2. (ii) Atropine
   3. (iii) Propranolol
   4. (iv) Hyoscine

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   OR
   (b) Classify the adrenergic agents with examples. Write their actions on
   1. (i) Heart,
   2. (ii) Bronchioles,
   3. (iii) Intestine and
   4. (iv) Eye.

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   Add a note on their therapeutic uses. (4+8+2)
3. (a) Write about the classification of anti-depressant agents. Write in detail about the mechanism of action, therapeutic uses and adverse reactions of SSRIs. (6+8)
   OR
   (b) Define Parkinsonism. Classify anti-Parkinson's drugs with examples? Write the mechanism of action and therapeutic uses of COMT inhibitors and MAO inhibitors. (2+6+6)
4. (a) Define arrhythmias. Classify the anti-arrhythmic agents. Discuss the pharmacology of any two drugs of different classes. (2+6+6)
   

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   OR
   (b) What is bronchial asthma? Classify anti-asthmatic drugs. Explain the pharmacology of any two drugs. (2+4+8)
5. (a) Define Diuresis. Classify Diuretics and explain mechanism of action, adverse reactions and therapeutic uses of carbonic anhydrase inhibitors and potassium sparing diuretics. (2+5+7)
   OR
   (b) Write about the pharmacology of Purgatives. (6)
   

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   (c) Write the mechanism of action and therapeutic uses of following drugs: (8)
   1. (i) Ondansetron
   2. (ii) Pantoprazole

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