Download OU B.Pharma 3-1 Year 2018 1184 Pharmacoloy I Question Paper

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Code No. 1184

FACULTY

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B. Pharmacy 3/4 I Semester (Suppl.) Examination, April 2018

Subject : Pharmacology -1

Time : 3 Hrs Max. Marks: 70

Note: Answer all questions. All questions carry equal marks.

1. (a) What are different routes of drug administration? Explain the merits and demerits of oral and parenteral routes of administration. (2+6)
   

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   (b) Define the following: (6)
   1. Therapeutic Index
   2. Biological Half life
   3. Tachyphylaxis
   
   OR
   

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   (c) Define and classify the receptors. Explain in detail about ion channel linked receptors. (2+5)
   (d) Write about different types of Phase I reactions. (7)
2. (a) Explain the pharmacological effects and therapeutic uses of : (5+5+4)
   1. Prazosin
   2. Atropine
   3. Proponolol

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   OR
   (b) Classify the cholinergic agents with examples. Write their actions on :
   1. Heart
   2. Bronchioles
   3. Intestine

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   4. Eye
   Add a note on their therapeutic uses. (4+8+2)
3. (a) Write about the classification of anti-depressant agents. Write in detail about the mechanism of action, therapeutic uses and adverse reactions of tricyclic antidepressants. (6+8)
   OR
   (b) Classify anti-epileptic agents and explain the mechanism of action and therapeutic uses of any three classes of drugs. (5+9)

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4. (a) Define Hyperlipidemia. Classify the anti-hyperlipidemic agents. Discuss the mechanism of action and therapeutic uses of any two drugs of different classes. (2+4+8)
   OR
   (b) What is bronchial asthma? Classify anti-asthmatic drugs. Explain the pharmacology of any two drugs. (2+4+8)
5. (a) Define Diuresis. Classify Diuretics and explain mechanism of action, adverse reactions and therapeutic uses of furosemide and spironolactone. (2+6+6)
   OR
   

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   (b) Write short notes on the pharmacology of: (7+7)
   1. H2 receptor blockers
   2. Anti-diarrhoeals

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