lOMoARcPSD|55903010
Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination January-2025
Subject- Pathology
Paper- II (new scheme)
Maximum Marks :100
Instructions:
a)
b)
Draw diagrams wherever necessary
c)
Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
MCQ has to be answered in theory answer book
e)
Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
counted in marks and action will be taken according to UFM rules of university.
g)
Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
10 x 1 = 10
1. Which virus is not transmitted parenterally?
(a) Hepatitis B
(b) Hepatitis C
(d) Hepatitis E
2. In which condition are Aschoff bodies seen?
(a) Rheumatoid arthritis
(b) Tuberculosis
(d) Sarcoidosis
disease
3. The most common primary site for the origin of Paget's disease is:
(a) Nipple
(c) Liver
(d) Penis
4. Which of the following is the most common cause of myocardial infarction?
(a) Hypertension
(c) Aortic stenosis
(d) Pulmonary embolism
thrombosis
5. In which of the following conditions are Reed-Sternberg cells seen?
(b) Hodgkin lymphoma
(c) Chronic lymphocytic
(d) Multiple myeloma
lymphoma
6. Hypothyroidism is associated with all of the following except:
(a) Cretinism
(b) Autism
(c) Cold intolerance
7. Not a germ cell tumor:
(a) Seminoma
(b) Yolk sac tumor
(c) PNET
8. Tamm-Horsfall protein is produced by:
(a) Distal tubules
(b) Ureter
(c) Loop of Henle
9. Multiple sclerosis is an autoimmune disease that affects the:
(a) Brain
(b) Spinal cord
(c) Peripheral nerves
10. Most common cause of Nephrotic syndrome in children is:
(a) RPGN
(b) PSGN
(c) Minimal change disease (d) Focal GN
lOMoARcPSD|55903010
Q2. Long Answer Questions
2 x 20 = 40
a. A 52-year-old woman presents with a palpable lump in her right breast. On examination, the lump is hard,
irregular, and fixed to the underlying tissue. There are palpable axillary lymph nodes. A mammogram shows a
I.
Based on the clinical presentation and imaging findings, what is the most likely histological diagnosis? (05
Mark)
II.
III.
Describe the significance of immune histochemical staining in the diagnosis and prognosis of breast
carcinoma. (05 Mark)
IV.
b. A middle-aged known smoker presented with persistent cough with expectoration and evening raise in
temperature in the past two weeks. Chest x ray identified consolidation in the lower portion of the upper lobe
of right lung. Hilar lymphadenopathy was noted. Sputum examination detected acid fast bacilli.
I.
II.
Discuss the pathogenesis. (5marks)
III.
Describe the gross and microscopic findings (5 marks)
Mention two complications (5marks)
Q3. Brief Answer Questions
6 x 05 = 30
a. What are the common causes of anemia, and how are they classified based on their morphology and
b. Discuss the diagnostic pathologic criteria of rheumatic heart disease
c. Enumerate the CSF findings in tuberculous meningitis
d. Describe in detail about melanoma?
e. How does hypertension lead to left ventricular hypertrophy?
Q4. Short Answer Questions
10 x 2 = 20
a. Describe various types of giant cells?
b. Paraneoplastic Syndrome
d. Explain the characteristic renal histopathological finding in diabetic nephropathy and its clinical significance.
e. Mention four causes of Congenital Hyperbilirubinemia
f. Write the gene involved in retinoblastoma?
g. Enumerate HPV associated malignancies
i. Write the battery of test for viral hepatitis?
j. Wilms Tumor
Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination January-2025
Subject- Pathology
Paper- II (new scheme)
--- Content provided by FirstRanker.com ---
Time: 3:00 HoursMaximum Marks :100
Instructions:
a)
--- Content provided by FirstRanker.com ---
All questions are compulsoryb)
Draw diagrams wherever necessary
c)
Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
--- Content provided by FirstRanker.com ---
d)MCQ has to be answered in theory answer book
e)
Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
--- Content provided by FirstRanker.com ---
MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not becounted in marks and action will be taken according to UFM rules of university.
g)
Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
--- Content provided by FirstRanker.com ---
Q1. Total MCQs: 1010 x 1 = 10
1. Which virus is not transmitted parenterally?
(a) Hepatitis B
(b) Hepatitis C
--- Content provided by FirstRanker.com ---
(c) Hepatitis G(d) Hepatitis E
2. In which condition are Aschoff bodies seen?
(a) Rheumatoid arthritis
(b) Tuberculosis
--- Content provided by FirstRanker.com ---
(c) Rheumatic heart(d) Sarcoidosis
disease
3. The most common primary site for the origin of Paget's disease is:
(a) Nipple
--- Content provided by FirstRanker.com ---
(b) Anal canal(c) Liver
(d) Penis
4. Which of the following is the most common cause of myocardial infarction?
(a) Hypertension
--- Content provided by FirstRanker.com ---
(b) Coronary artery(c) Aortic stenosis
(d) Pulmonary embolism
thrombosis
5. In which of the following conditions are Reed-Sternberg cells seen?
--- Content provided by FirstRanker.com ---
(a) Non-Hodgkin(b) Hodgkin lymphoma
(c) Chronic lymphocytic
(d) Multiple myeloma
lymphoma
--- Content provided by FirstRanker.com ---
leukemia6. Hypothyroidism is associated with all of the following except:
(a) Cretinism
(b) Autism
(c) Cold intolerance
--- Content provided by FirstRanker.com ---
(d) Weight gain7. Not a germ cell tumor:
(a) Seminoma
(b) Yolk sac tumor
(c) PNET
--- Content provided by FirstRanker.com ---
(d) Dysgerminoma8. Tamm-Horsfall protein is produced by:
(a) Distal tubules
(b) Ureter
(c) Loop of Henle
--- Content provided by FirstRanker.com ---
(d) Collecting duct9. Multiple sclerosis is an autoimmune disease that affects the:
(a) Brain
(b) Spinal cord
(c) Peripheral nerves
--- Content provided by FirstRanker.com ---
(d) Muscles10. Most common cause of Nephrotic syndrome in children is:
(a) RPGN
(b) PSGN
(c) Minimal change disease (d) Focal GN
--- Content provided by FirstRanker.com ---
lOMoARcPSD|55903010
Q2. Long Answer Questions
2 x 20 = 40
a. A 52-year-old woman presents with a palpable lump in her right breast. On examination, the lump is hard,
irregular, and fixed to the underlying tissue. There are palpable axillary lymph nodes. A mammogram shows a
--- Content provided by FirstRanker.com ---
mass with micro calcifications. A biopsy is performed.I.
Based on the clinical presentation and imaging findings, what is the most likely histological diagnosis? (05
Mark)
II.
--- Content provided by FirstRanker.com ---
What are the key prognostic factors for breast carcinoma? (05 Mark)III.
Describe the significance of immune histochemical staining in the diagnosis and prognosis of breast
carcinoma. (05 Mark)
IV.
--- Content provided by FirstRanker.com ---
What are the histological features of Paget's disease of the breast? (05 Mark)b. A middle-aged known smoker presented with persistent cough with expectoration and evening raise in
temperature in the past two weeks. Chest x ray identified consolidation in the lower portion of the upper lobe
of right lung. Hilar lymphadenopathy was noted. Sputum examination detected acid fast bacilli.
I.
--- Content provided by FirstRanker.com ---
What is the most probable diagnosis? (5marks)II.
Discuss the pathogenesis. (5marks)
III.
Describe the gross and microscopic findings (5 marks)
--- Content provided by FirstRanker.com ---
IV.Mention two complications (5marks)
Q3. Brief Answer Questions
6 x 05 = 30
a. What are the common causes of anemia, and how are they classified based on their morphology and
--- Content provided by FirstRanker.com ---
etiology?b. Discuss the diagnostic pathologic criteria of rheumatic heart disease
c. Enumerate the CSF findings in tuberculous meningitis
d. Describe in detail about melanoma?
e. How does hypertension lead to left ventricular hypertrophy?
--- Content provided by FirstRanker.com ---
f. Enlist the Classification of ovarian tumorsQ4. Short Answer Questions
10 x 2 = 20
a. Describe various types of giant cells?
b. Paraneoplastic Syndrome
--- Content provided by FirstRanker.com ---
c. Enlist histopathological features of Papillary of Carcinoma thyroidd. Explain the characteristic renal histopathological finding in diabetic nephropathy and its clinical significance.
e. Mention four causes of Congenital Hyperbilirubinemia
f. Write the gene involved in retinoblastoma?
g. Enumerate HPV associated malignancies
--- Content provided by FirstRanker.com ---
h. Write all the parameters of complete blood count report (CBC)?i. Write the battery of test for viral hepatitis?
j. Wilms Tumor