lOMoARcPSD|55903010
Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination April-2024
Subject- Pharmacology
Paper- II (new scheme)
Maximum Marks :100
Instructions:
a)
b)
Draw diagrams wherever necessary
c)
Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
MCQ has to be answered in theory answer book
e)
Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
counted in marks and action will be taken according to UFM rules of university.
g)
Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
10 x 1 = 10
1. Which of the following drug is approved by FDA for generalized HSDD (Hypoactive sexual disorder in
premenopausal women):
(a) Flibanserin
(c) Finasteride
(d) Clomiphene
2. All of the following drugs are used for treating alcohol use disorder (AUD), EXCEPT:
(a) Disulfiram
(c) Fomepizole
(d) Acamprostate
3. Which of the following is the most common paradoxical side effect of Indomethacin:
(a) Hypersensitivity
(c) Frontal headache
(d) Nephropathy
4. Which of the following drug used for Acute Toxoplasmosis during early pregnancy:
(a) Spiramycin
(c) Sulfadiazine
(d) Pyrimethamine
5. Which of the following drugs is used for treatment of Neurocysticercosis:
(a) Mebendazole
(c) Albendazole
(d) Tinidazole
6. Which of following antiviral is used for the treatment of corona virus:
(a) Cidofovir
(c) Amantadine
(d) Remdesivir
7. All of the following drugs inhibit the peripheral conversion of T4 to T3, EXCEPT:
(a) Methimazole
(c) Propranolol
(d) Dexamethasone
8. All of the following drugs are used in the treatment of osteoporosis, EXCEPT:
(a) Bisphosphonate
(c) Tamoxifen
(d) Calcitonin
9. Which of the following Cephalosporins has allergic cross reactivity with Aztreonam:
(a) Ceftazidime
(c) Ceftriaxone
(d) Cefotaxime
10. Which of the following drug is effective in both grand mal and petit mal epilepsy:
(a) Phenobarbitone
(c) Phenytoin
(d) Carbamazepine
lOMoARcPSD|55903010
Q2. Long Answer Questions
a. A 30-year-old mother comes to OPD. On history taking, she had 4 months baby and lactating. She wanted to
space out her next child and consulting you for taking contraceptive pills.
I Which type of hormonal contraceptive would you suggest?
II Enumerate Adverse effect and Contraindication of oral contraceptive pills.
IV Write basis used of clomiphene in infertility.
b. A 47-year-old man attends neurology clinic with complaints of resting tremors of right hand and arm. He
moves slowly and has diminished range of facial expressions. His speech is slow and monotonous. He is
diagnosed to be suffering from early stage of Parkinson's disease. He was prescribed levodopa/Carbidopa
I Explain the rationale of combining levodopa with carbidopa and what are the advantages of combination.
II Classify Antiparkinsonian drugs.
III What are advantages of dopamine receptor agonists over levodopa/carbidopa combination.
IV Enumerate drugs causing Parkinsonism and write treatment of drug-induced Parkinsonism.
6 x 05 = 30
a. Enumerate 3rd generation Cephalosporins & write their therapeutic uses and adverse effects.
b. Enumerate Atypical antipsychotics. Write their advantages over typical antipsychotics.
c. Enumerate nonsteroidal anti-inflammatory drugs (NSAID). Write basis of use of Paracetamol as antipyretic.
e. Enumerate SSRIs & write rationale for use of Fluoxetine in depression.
f. Enumerate drugs for MDR & XDR tuberculosis. Write basis of combination therapy in tuberculosis.
Q4. Short Answer Questions
10 x 2 = 20
b. Abrupt withdrawal of glucocorticoids after prolonged therapy is not advised, why?
c. Enumerate 04 drugs used in prophylaxis of migraine.
d. Write drug used in anaerobic infection.
e. Write drug used is Staphylococcal infection.
g. Write drugs for chloroquine resistant P. falciparum malaria.
h. Write notes on fluoroquinolones.
i. Write basis of use of valproate in epilepsy.
j. Why morphine is contraindicated in patients having head injury.
Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination April-2024
Subject- Pharmacology
Paper- II (new scheme)
--- Content provided by FirstRanker.com ---
Time: 3:00 HoursMaximum Marks :100
Instructions:
a)
--- Content provided by FirstRanker.com ---
All questions are compulsoryb)
Draw diagrams wherever necessary
c)
Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
--- Content provided by FirstRanker.com ---
d)MCQ has to be answered in theory answer book
e)
Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f)
--- Content provided by FirstRanker.com ---
MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not becounted in marks and action will be taken according to UFM rules of university.
g)
Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
--- Content provided by FirstRanker.com ---
Q1. Total MCQs: 1010 x 1 = 10
1. Which of the following drug is approved by FDA for generalized HSDD (Hypoactive sexual disorder in
premenopausal women):
(a) Flibanserin
--- Content provided by FirstRanker.com ---
(b) Mifepristone(c) Finasteride
(d) Clomiphene
2. All of the following drugs are used for treating alcohol use disorder (AUD), EXCEPT:
(a) Disulfiram
--- Content provided by FirstRanker.com ---
(b) Naltrexone(c) Fomepizole
(d) Acamprostate
3. Which of the following is the most common paradoxical side effect of Indomethacin:
(a) Hypersensitivity
--- Content provided by FirstRanker.com ---
(b) Peptic ulcer(c) Frontal headache
(d) Nephropathy
4. Which of the following drug used for Acute Toxoplasmosis during early pregnancy:
(a) Spiramycin
--- Content provided by FirstRanker.com ---
(b) Clindamycin(c) Sulfadiazine
(d) Pyrimethamine
5. Which of the following drugs is used for treatment of Neurocysticercosis:
(a) Mebendazole
--- Content provided by FirstRanker.com ---
(b) Metronidazole(c) Albendazole
(d) Tinidazole
6. Which of following antiviral is used for the treatment of corona virus:
(a) Cidofovir
--- Content provided by FirstRanker.com ---
(b) Ganciclovir(c) Amantadine
(d) Remdesivir
7. All of the following drugs inhibit the peripheral conversion of T4 to T3, EXCEPT:
(a) Methimazole
--- Content provided by FirstRanker.com ---
(b) Propylthiouracil(c) Propranolol
(d) Dexamethasone
8. All of the following drugs are used in the treatment of osteoporosis, EXCEPT:
(a) Bisphosphonate
--- Content provided by FirstRanker.com ---
(b) Raloxifine(c) Tamoxifen
(d) Calcitonin
9. Which of the following Cephalosporins has allergic cross reactivity with Aztreonam:
(a) Ceftazidime
--- Content provided by FirstRanker.com ---
(b) Ceftaroline(c) Ceftriaxone
(d) Cefotaxime
10. Which of the following drug is effective in both grand mal and petit mal epilepsy:
(a) Phenobarbitone
--- Content provided by FirstRanker.com ---
(b) Sodium valproate(c) Phenytoin
(d) Carbamazepine
lOMoARcPSD|55903010
Q2. Long Answer Questions
--- Content provided by FirstRanker.com ---
2 x 20 = 40a. A 30-year-old mother comes to OPD. On history taking, she had 4 months baby and lactating. She wanted to
space out her next child and consulting you for taking contraceptive pills.
I Which type of hormonal contraceptive would you suggest?
II Enumerate Adverse effect and Contraindication of oral contraceptive pills.
--- Content provided by FirstRanker.com ---
III Write regimens used as Emergency contraceptives.IV Write basis used of clomiphene in infertility.
b. A 47-year-old man attends neurology clinic with complaints of resting tremors of right hand and arm. He
moves slowly and has diminished range of facial expressions. His speech is slow and monotonous. He is
diagnosed to be suffering from early stage of Parkinson's disease. He was prescribed levodopa/Carbidopa
--- Content provided by FirstRanker.com ---
250mg/25mg four times daily.I Explain the rationale of combining levodopa with carbidopa and what are the advantages of combination.
II Classify Antiparkinsonian drugs.
III What are advantages of dopamine receptor agonists over levodopa/carbidopa combination.
IV Enumerate drugs causing Parkinsonism and write treatment of drug-induced Parkinsonism.
--- Content provided by FirstRanker.com ---
Q3. Brief Answer Questions6 x 05 = 30
a. Enumerate 3rd generation Cephalosporins & write their therapeutic uses and adverse effects.
b. Enumerate Atypical antipsychotics. Write their advantages over typical antipsychotics.
c. Enumerate nonsteroidal anti-inflammatory drugs (NSAID). Write basis of use of Paracetamol as antipyretic.
--- Content provided by FirstRanker.com ---
d. Write notes on SGLT-2 inhibitors.e. Enumerate SSRIs & write rationale for use of Fluoxetine in depression.
f. Enumerate drugs for MDR & XDR tuberculosis. Write basis of combination therapy in tuberculosis.
Q4. Short Answer Questions
10 x 2 = 20
--- Content provided by FirstRanker.com ---
a. Explain oxytocin is preferred over ergometrine for induction of labour.b. Abrupt withdrawal of glucocorticoids after prolonged therapy is not advised, why?
c. Enumerate 04 drugs used in prophylaxis of migraine.
d. Write drug used in anaerobic infection.
e. Write drug used is Staphylococcal infection.
--- Content provided by FirstRanker.com ---
f. Explain Lugol's iodine is used prior to thyroid surgery.g. Write drugs for chloroquine resistant P. falciparum malaria.
h. Write notes on fluoroquinolones.
i. Write basis of use of valproate in epilepsy.
j. Why morphine is contraindicated in patients having head injury.
--- Content provided by FirstRanker.com ---