Madhya Pradesh Medical Science University, Jabalpur
MBBS Second Professional Examination 2022
Subject- Pharmacology
Time: 3:00 Hours
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Paper- IMaximum Marks :100
Instructions:
a)
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All questions are compulsoryb)
Draw diagrams wherever necessary
c)
Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
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d)Do not write anything on the blank portion of question paper, if written anything such type of act will be considered as an attempt to resort to unfair means
Q1. Long Answer questions
2 X 10 = 20
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a. 30-year-old female patient comes to OPD with complaints of headache, dizziness andpalpitations. On examination the pulse rate was found to be 110min and BP-160/100 mmHg. The
patient was diagnosed to have essential hypertension.
a. Classify antihypertensive drugs.
b. Role of B-blockers in the treatment of hypertension.
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c. Role of Diuretics in the treatment of hypertension.d. Role of ACE inhibitors in the treatment of hypertension
e. Which drugs are used for treatment of hypertensive crisis?
f. Which antihypertensive drugs are safe during pregnancy?
b. Classify B- adrenergic receptor blockers. Describe pharmacological actions, therapeutic uses
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and adverse effects of ?- adrenergic receptor blockers.Q2. Short Answer Questions
4 X 5= 20
a. Prokinetic Drugs.
b. HMG COA reductase inhibitors.
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c. Mechanism of action & therapeutic uses of proton pump inhibitors.d. Drug therapy of myocardial infarction.
e. Clinical significance of plasma half-life.
f. Describe the role of physician in health care system.
Q3. Very Short Answer Questions
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1 X 10= 10a. Justify use of epinephrine in anaphylactic shock.
b. Why low dose dopamine is used in acute renal failure?
c. Differences between d-tubocurarine & succinylcholine.
d. Why antihistamines are not used for treatment of bronchial asthma?
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e. Why low dose aspirin is used as antiplatelet agent?f. Explain the pharmacological basis of using lactulose in hepatic coma.
g. Describe mechanism of action of warfarin as anticoagulant agent.
h. Explain why amiodarone is called broad spectrum antiarrhythmic agent?
i. Mention important advantages & disadvantages of prodrug.
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j. Justify use of frusemide in acute left ventricular failure.