2406000102020601-S
(SUPPLIMENTARY EXAM) FEBRUARY-2025
SECOND MBBS
PATHOLOGY ( PAPER - I ) ( NEW ) (OMR)
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[Time: As Per Schedule][Max. Marks:100]
Instructions:
Seat No:
1. Fill up strictly the following details on your answer book
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a. Name of the Examination: SECOND MBBSb. Name of the Subject: PATHOLOGY (PAPER - I) (NEW)
(OMR)
c. Subject Code No: 2406000102020601-S
2. Sketch neat and labelled diagram wherever necessary.
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3. Figures to the right indicate full marks of the question.4. All questions are compulsory.
Student's Signature
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SECTION -IQ.1 Multiple choice questions (*no negative markings)
20
Each Question Carries One mark.
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1. All infarcts are usually:A. Wedge shaped.
B. Square shaped
C. Rectangular shaped
D. Circular in shape
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2. Most common opportunistic lung infection in AIDS patient isA. Pneumocystis carinii
B. Kaposi sarcoma
C. candidiasis
D. Histoplasmosis.
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3. IgE mediated allergy / Asthma is example of which hypersensitivityreaction
A. Type-l
B. Type-II
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[1 of 5]C. Type-III
D. Type-IV.
4. The most common route of spread of infection to the brain is:
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A. Via venous routeB. Via arterial route
C. Via lymphatics
D. Along nerves
5. Test useful for detection of HIV during window period:
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A. ELISAB. Western blot
C. CD4+ cell count
D. p24 antigen capture assay
6. Dystrophic calcification in Spleen is seen in which disease.
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A. Sickle cell diseaseB. Left Heart Failure
C. Fatty Liver
D. ARDS.
7. Diabetic foot is an example of:
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A. Dry gangreneB. Wet gangrene
C. Gas gangrene
D. Necrotising inflammation
8. Interstitial fluid collection during Congestive cardiac failure is called
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A. Cystic collectionB. Exudate
C. Edema
D. Effusion.
9. Haematoxylin stains:
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A. Nuclear chromatin material B. RNAC. Cytosolic components
D. Cell membrane components.
10. Most Important Antigen initiating graft rejection.
A. P24 Ag
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B. polysaccharideC. HLA antigen
D. TCR.
11. Type of Necrosis in pancreatitis:
A. Fat
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B. Fibrinoid2406000102020601-S
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C. Caseus
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D. Coagulative12. Which of the following is an Apoptosis inhibitor gene?
A. BCL-2
B. Rb
C. P53
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D. C-Myc13. Out of various free radical species, the following radical is most
reactive:
A. Superoxide (O2')
B. Hydrogen peroxide (H2O2)
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C. Hydroxyl (OH-)D. Nitric oxide (NO)
14. Correct sequence of Cell cycle is
A. G0-M-G2-S-G1
B. G0-G1-G2-S-M
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C. G0-G1-S-G2-MD. G0-G1-S-M-G2
15. For karyotyping, the dividing cells are arrested by Addition of
colchicine in the following mitotic phase:
A. Prophase
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B. MetaphaseC. Anaphase
D. Telophase
16. For Electron Microscopy Histopathology specimen are fixed in
A. Glutaraldehyde
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B. 10% Ethyl alcoholC. 10% picric acid
D. 10% buffered neutral formalin
17. Enzyme which prevents ageing is:
A. Catalase
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B. Superoxide dismutaseC. Metalloproteinase
D. Telomerase
18. Bombay Blood group person have following ABO Blood group
A. "A" group
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B. "B" groupC. "O" group
D. "H" group
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19. Basement membrane consists of:
A. Type I collagen
B. Type II collagen
C. Type III collagen
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D. Type IV collagen20. All are autosomal dominant inherited cancer syndromes except:
A. Retinoblastoma
B. Xeroderma pigmentosum
C. HNPCC
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D. Neurofibromatosis.SECTION -II
Q.2 Case based long essay questions
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[13*1=13]A 40-year-old male who had a history of road traffic accident presented to the
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clinic with polytrauma and left thigh swelling.Patient was not able to walk.
His x-ray showed comminuted displaced fracture of the shaft femur. After 2
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days he developed sudden shortness of breath, confusion, and vomiting, He
also developed petechial rashes
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Lab findings - microscopic examination of urine showed fat globules.1) What is your diagnosis based on the above clinical finding and lab
02
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investigation?
02
2) Describe aetiology and pathogenesis of given condition
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3) Write consequences of given condition04
4) Describe difference between Arterial thrombi and Venous thrombi
05
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Q.3 Long essay questions. (Attempt any three)9*3=27
1) Define oedema. Discuss pathophysiology of oedema. Add a note on
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[4+3+2]pulmonary oedema.
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2) Define Hypersensitivity reactions. Describe etiology, pathogenesis, and
[1+2+4+2]
examples of Type- 4 Hypersensitivity reactions.
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3) Define Inflammation. Write in detail about vascular and cellular
[4+3+2]
changes in inflammation.
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4) Describe etiology of Cell injury. Describe morphology of Cell injury.[3+6]
SECTION-III
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Q.4 Short notes (Attempt Any 8)[8*5=40]
1) Three opportunistic infections and two neoplasms associated with
AIDS.
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2) Microscopic Findings of Urine in Various Diseases.3) Describe CSF picture in Pyogenic meningitis.
4) Down's syndrome.
5) Viral oncogenesis.
6) Septic shock
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7) Enumerate Blood components and mention their uses and storage.8) Granulomatous inflammation.
9) Etiopathology and sequelae of Obesity.
10) FISH (Fluorescence in situ Hybridization).
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