Download VNSGU MBBS 2nd Year 2024 January New 2406000102030701 Microbiology Paper I Feb 2025 mcq Question Paper

2406000102030701-S
(SUPPLIMENTARY EXAM) FEBRUARY-2025
SECOND MBBS
MICROBIOLOGY ( PAPER - I ) ( NEW ) (OMR)

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[Time: As Per Schedule]
[Max. Marks:100 ]
Instructions:
Seat No:
1. Fill up strictly the following details on your answer book

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a. Name of the Examination: SECOND MBBS
b. Name of the Subject: MICROBIOLOGY (PAPER - I) (NEW)
(OMR)
c. Subject Code No: 2406000102030701-S
2. Sketch neat and labelled diagram wherever necessary.

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3. Figures to the right indicate full marks of the question.
4. All questions are compulsory.
Student's Signature

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SECTION-I
Q.1 Multiple Choice Questions (MCQ)
20

1. Which of the following is a Gram-positive cocci that grows in clusters?

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A. Staphylococcus aureus
B. Streptococcus pyogenes
C. Neisseria meningitidis
D. Escherichia coli
2. The classical pathway of complement activation is triggered by:

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A. Lipopolysaccharides
B. Antigen-antibody complexes
C. Lectins binding to pathogens
D. Alternative surface molecules
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3. The vector for transmission of malaria is:
A. Culex mosquito
B. Aedes mosquito

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C. Anopheles mosquito
D. Sandfly
4. The primary site of replication for Hepatitis B virus is:
A. Pancreas
B. Intestine

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C. Liver
D. Spleen
5. Escherichia coli is most commonly associated with:
A. Skin infections
B. Urinary tract infections

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C. Meningitis
D. Endocarditis
6. Which immunoglobulin is present in the highest concentration in serum?
A. IgA
B. IgE

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C. IgM
D. IgG
7. The causative agent of typhoid fever is:
A. Salmonella typhi
B. Vibrio cholerae

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C. Shigella dysenteriae
D. Clostridium perfringens
8. Which of the following is an anaerobic Gram-positive rod?
A. Clostridium difficile
B. Pseudomonas aeruginosa

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C. Klebsiella pneumoniae
D. Proteus mirabilis
9. Which hepatitis virus is most commonly transmitted via the fecal-oral
route?
A. Hepatitis B

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B. Hepatitis C
C. Hepatitis D
D. Hepatitis A
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10. Which organism is a common cause of bacterial endocarditis on
prosthetic valves?
A. Staphylococcus epidermidis B. Staphylococcus aureus
C. Escherichia coli

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D. Enterococcus faecalis
11. The Widal test is used for diagnosing:
A. Cholera
B. Enteric fever
C. Tuberculosis

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D. Dengue fever
12. Which immunological cell type is primarily involved in granuloma
formation?
A. Neutrophils
B. Macrophages

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C. T lymphocytes
D. Plasma cells
13. The causative organism of amoebic dysentery is:
A. Giardia lamblia
B. Entamoeba histolytica

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C. Cryptosporidium parvum
D. Shigella dysenteriae
14. The toxin responsible for the symptoms of tetanus acts on:
A. Peripheral nerves
B. Neuromuscular junctions

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C. Central nervous system
D. Skeletal muscles
15. The characteristic stool appearance in cholera is described as:
A. Bloody stool
B. Rice water stool

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C. Mucus-filled stool
D. Foamy stool
16. Which test is commonly used to detect antibodies in autoimmune
diseases?
A. ELISA

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B. Coombs test
C. Immunofluorescence assay D. Western blot
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17. Helicobacter pylori is most commonly associated with:
A. Gastric ulcers
B. Diarrhea
C. Liver abscess
D. Pancreatitis

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18. A common cause of bacterial peritonitis in cirrhotic patients is:
A. Escherichia coli
B. Klebsiella pneumoniae
C. Enterococcus faecalis
D. Salmonella typhi

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19. The Ziehl-Neelsen stain is used to identify:
A. Gram-negative bacteria
B. Acid-fast bacilli
C. Fungi
D. Parasites

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20. Rocky mountain snotted fever is due to
A. R. rickettsii
B. R. prowazekii
C. R. typhi
D. R. conoril

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SECTION-II
Q.2 Essay-type Question.
12

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Describe in detail about the structure and function of various lymphoid organs
and cells of immune system.
Q.3 Answer in Brief (Any 4 out of 5)
28
1. Describe the differences between innate and adaptive immunity.

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2. Describe in detail the structure & Function of the Bacterial Cell
wall~write methods of Demonstration of cell wall.
3. Write a short note on the mechanism of action of bacterial endotoxins.
4. Draw the two common complement activation pathways and describe
the importance of complement in health and disease.

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5. Replication of viruses.
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SECTION-III

Q.4 Essay-type Question.
12

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A 35-year-old male presents with high-grade fever, fatigue, and new onset of a

heart murmur. Blood culture grows Streptococcus viridans.

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1. What is the likely clinical condition?
02
2. Discuss the pathogenesis of this condition.
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3. Describe the laboratory diagnosis and treatment options.
05
Q.5 Answer in Brief (Any 4 out of 5)
28
1. Pyrexia of unknown origin: definition, causes and diagnostic test used

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2. Explain the pathogenesis and clinical features of amoebic liver abscess.
3. Discuss the role of Helicobacter pylori in peptic ulcer disease.
4. Explain the laboratory diagnosis of Hepatitis B virus infection
5. Importance of effective communication skills in Doctor-Patient
relationship.

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