Download GTU B.Pharma 2018 Summer 3rd Sem 230005 Pathophysiology Question Paper

Download GTU (Gujarat Technological University) B.Pharma (Bachelor of Pharmacy) 2018 Summer 3rd Sem 230005 Pathophysiology Previous Question Paper

Seat No.: _____ Enrolment No. _____________
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER?3 ? EXAMINATION ? SUMMER -2018

Subject Code: 230005 Date: 07/05/2018
Subject Name: Pathophysiology
Time: 02:30 PM TO 05:30 PM
Total Marks: 80

Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary
3. Figures to the right indicate full marks

Q.1
(a) Discuss the cellular and molecular mechanism of reversible and
06
irreversible cell injury due to ischaemia.

(b) Describe causes and pathological changes underlying atrophy.
05

(c) Write a note on tissue regeneration process.
05


Q.2
(a) Define apoptosis. Describe causes, molecular mechanism and
06
importance of apoptosis.

(b) Discuss in detail about on Amyloidosis.
05

(c) Write a note on components of extracellular matrix.
05


Q.3
(a) Define radiation injury. Explain mechanisms involved in radiation
06
induced damage to the DNA of cell.

(b) Write a note on pathogenesis of rheumatoid arthritis.
05

(c) Write note on HLA system and its importance
05


Q.4
(a) Enlist various hypersensitivity reactions. Discuss mechanisms
06
involved in cell mediated immunity.

(b) Describe cellular events in acute inflammation. Explain chemotaxis.
05

(c) Write a note on wound healing process.
05


Q.5
(a) Define autoimmunity and classify autoimmune disease. Write a note 06
on Systemic Lupus Erythematosus.

(b) Describe the role of different systems in generation of plasma
05
derived mediators.

(c) Write in detail about effector mechanism of graft rejection.
05


Q. 6
(a) Discuss the cells of immune system and their function.
06

(b) Write in detail about pathogenesis of HIV infections.
05

(c) Explain pathogenesis of calcification
05


Q.7
(a) Write about etiology of obesity. Explain its metabolic changes.
06

(b) Discuss pathogenesis of nutritional deficiency diseases.
05

(c) Write a note on therapeutic drug induced adverse reactions.
05
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