Seat No.:
Subject Code: 2260005
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Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER-6 * EXAMINATION — SUMMER -2018
Subject Name: Pharmacology and Pharmacotherapeutics-I1
Time: 10:30 AM TO 01:30 PM
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Instructions:
- Attempt any five questions.
- Make suitable assumptions wherever necessary.
- Figures to the right indicate full marks.
Q.1 | (a) | Discuss pathophysiology and pharmacotherapeutic management of Schizophrenia. | 06 |
(b) | Classify CNS Stimulants. Explain mechanism of action and therapeutic uses of Amphetamine | 05 | |
(c) | Write a note on etiology and treatment of Gout. | 05 | |
Q.2 | (a) | Discuss briefly: (i) Psychological dependence (i1) Drug induced reward (iii) Drug abuse. | 06 |
(b) | List out ideal properties of general anesthetics. Describe different stages of general anesthesia. | 05 | |
(c) | Write clinical manifestations and pharmacotherapeutic management of Mania. | 05 | |
Q.3 | (a) | Classify opioid analgesics. Discuss about opioid antagonists with reference to opioid receptors. | 06 |
(b) | Explain pathophysiology and treatment of Alzheimer’s disease. | 05 | |
(c) | Explain mechanisms of tolerance development with suitable examples. | 05 | |
Q.4 | (a) | Classify immunosuppressants. Write mechanism of action, therapeutic uses and adverse effects of Tacrolimus. | 06 |
(b) | Write mechanism of action and therapeutic uses of the followings:
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(c) | Write a note on dopamine as a CNS neurotransmitter. | 05 | |
Q.5 | (a) | Classify NSAIDS. Explain Mechanism of action, therapeutic uses and adverse effects of Aspirin. | 06 |
(b) | Write a note on selective COX-II inhibitors. | 05 | |
(c) | Write a note on methyl alcohol poisoning and its treatment. | 05 | |
Q.6 | (a) | Describe pathophysiology of parkinsonism and justify the use of L-dopa and Carbidopa combination for treatment. | 06 |
(b) | Write briefly on management and treatment of anxiety. | 05 | |
(c) | Discuss therapeutic management of Grandmal epilepsy. | 05 | |
Q.7 | (a) | Describe etiology, signs and symptoms, diagnosis and treatment of Depression. | 06 |
(b) | Classify Hallucinogens. Discuss Cannabinoids as Hallucinogens. | 05 | |
(c) | Write a note on pre-anasthetic medications. | 05 |
Total Marks: 80
Date: 10/05/2018
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