Download Pharm-D (Doctor of Pharmacy) 1st Year (First Year) 2018 May 383804 Pharmaceutical Organic Chemistry Previous Question Paper
[LM 804] MAY 2018 Sub. Code: 3804
PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
FIRST YEAR
PAPER IV ? PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code : 383804
Time : Three hours Maximum : 70 Marks
I. Elaborate on: (4 x 10 = 40)
1. Explain the mechanism of nucleophilic aromatic substitution reactions, orientation
and reactivity of benzene.
2. Explain about the resonance stabilization of benzyl radical.
3. What are electrophilic addition reactions? Explain any two reactions in detail.
4. Explain the mechanisms of following name reactions:
a) Perkin condensation b) Kolbe reaction.
II. Write notes on: (6 x 5 = 30)
1. Give an account of acid and base on the basis of Lewis theory.
2. Explain the addition reaction of conjugated dienes.
3. Discuss about allylic rearrangement with examples.
4. Write the preparation, test for purity, assay and medicinal use of mephensin.
5. What are cycloalkanes? Give an example. Discuss the preparation of
cycloalkanes.
6. Illustrate a note on free radical chain reactions of alkane.
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