Download Pharm D 1st Year 2011 May 383804 Pharmaceutical Organic Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 1st Year (First Year) 2011 May 383804 Pharmaceutical Organic Chemistry Previous Question Paper

[KY 804] MAY 2011 Sub. Code: 3804
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(Regulations 2008-2009 )
(Candidates admitted from 2008-2009 onwards)
FIRST YEAR
PAPER IV ? PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
Answer ALL questions
I. Elaborate on: (2 x 20 = 40)
1. Describe the two mechanisms of aliphatic nucleophilic substitution reactions.
Compare and contrast these two reactions in detail.
2. Describe in detail free radical halogenation of methane explaining the thermodynamics
of the reaction with respect to the halogens: F, Cl, Br, & I.
II. Write notes on: (6 x 5 = 30)
1. Preparation, tests for purity, assay, and uses of Aspirin.
2. Aldol condensation and cyanohydrin reaction of aldehydes.
3. Explain Sandmeyer?s reaction with suitable examples.
4. Two methods of preparations of aldehydes.
5. Explain Schotten-Bauman reaction.
6. Write a note on the advantages of Friedal Crafts Acylation over Alkylation.
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