Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
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[LE 804] APRIL 2014 Sub. Code: 3804
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DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
FIRST YEAR
PAPER IV - PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
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Answer All questions
- Elaborate on: (2x20=40)
- What are Electrophilic addition reactions? Explain any two reactions in detail.
- Explain the mechanism and reactions of the following:
- Claisen condensation.
- Knoevenagel reaction.
- Perkin condensation.
- Kolbe reaction.
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- Write notes on: (10x 3 =30)
- Diel’s alder reaction.
- Discuss the mechanism and synthetic uses of Aldol condensation.
- Give an account of acid and base on the basis of Lewis theory.
- Give an example for free radical halogenation of alkenes with respect to carbon-carbon double bond acting as a substituent.
- Write a note on activating and deactivating Ortho, Para and Meta directing groups.
- Write any two methods of conversion of acid to esters.
- Riemer —Tiemann’s reaction.
- Write any two methods to prepare alkyl halides.
- Add a note on carbocations.
- Write the preparation, test for purity, Assay and uses of Saccharin.
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