Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LF 804] OCTOBER 2014 Sub. Code: 3804
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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(2009-2010 Regulation)
FIRST YEAR
PAPER 1V - PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
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Answer All questions
- Elaborate on: (4 x10=40)
- Discuss the reaction, mechanism of Nucleophilic aromatic substitution.
- Briefly discuss Stereochemistry of SN1 and SN2 reaction. How rearrangement take place in carbocation in Nucleophilic aliphatic substitution.
- Mention the reaction of conversion of acid to:
- Amide.
- Acid chloride.
- Esters.
- Anhydride.
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- Explain the following reaction with mechanism:
- Diazotisation and coupling.
- Aldol condensation.
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- Write notes on: (6x5=30)
- Explain the addition reaction of conjugated dienes.
- Write the structure, preparation, Assay and chemical uses of Sodium lauryl sulphate.
- Explain the Wittig reaction with mechanisms.
- Additions of carbene.
- Orbital picture of Allyl radical.
- Explain the mechanism of E1 and E2 reaction.
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