[LG 814] APRIL 2015 Sub. Code: 3814
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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(2009-2010 Regulation)
THIRD YEAR
PAPER 11 - PHARMACEUTICAL ANALYSIS
Q.P. Code: 383814
Time: Three Hours Maximum: 70 marks
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Answer All questions
- Elaborate on: (4 x10=40)
- With a neat labeled diagram, discuss the principle and various components of IR spectroscopy.
- Write the principle and various carrier gases used in GLC. Explain working principle of any two detectors used in GLC with a neat labeled diagram.
- Explain the principle and instrumentation of spectrofluorimeter with a neat diagram.
- Write the theoretical aspects, indicator and reference electrodes used, methods of detecting end point in potentiometry.
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- Write notes on: (6x5=30)
- State and explain fundamental laws of absorption. Write its deviations and reasons for the deviations.
- What are amperometric titrations? Add a note on advantages and applications of amperometric titrations.
- Write a note on DTA.
- What is validation? Give a brief account of validation of analytical methods.
- Describe the principle and various types of ion exchange resins used in ion exchange chromatography.
- Explain the principle involved in mass spectroscopy. List the various types of ions produced in mass spectrum.
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