Download Pharm D 3rd Year 2015 Oct 383817 Medicinal Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 3rd Year (Third Year) 2015 Oct 383817 Medicinal Chemistry Previous Question Paper

[LH 817] OCTOBER 2015 Sub. Code: 3817
PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
THIRD YEAR
PAPER V ? MEDICINAL CHEMISTRY
Q.P. Code : 383817
Time: Three Hours Maximum: 70 marks
Answer ALL questions
I. Elaborate on : (4 x 10 = 40)
1. Classify alkylating agents. Discuss in detail the mechanism of action and SAR of
alkylating agents.
2. Enumerate various electronic and solubility parameters in QSAR.
3. Describe briefly on various approaches of prodrug design.
4. Briefly discuss the mechanism of action and SAR of azole antifungals.
II. Write notes on : (6 x 5 = 30)
1. Write a short note on antihyperlipidemic agents.
2. Write the structure, mechanism of action and synthesis of pyrazinamide.
3. Write the structure and uses of any two diagnostic agents.
4. Write the structure, mechanism of action and synthesis of amantadine.
5. Write a short note on amino glycoside antibiotics.
6. Write a note on molecular mechanics.


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