Download Pharm D 3rd Year 2015 April 383817 Medicinal Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 3rd Year (Third Year) 2015 April 383817 Medicinal Chemistry Previous Question Paper

[LG 817] APRIL 2015 Sub. Code: 3817
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
THIRD YEAR
PAPER V ? MEDICINAL CHEMISTRY
Q.P. Code: 383817
Time: Three Hours Maximum: 70 marks
Answer All questions
I. Elaborate on: (4 x 10 = 40)
1. Classify diuretics.
Explain the mechanism of action and structure of any one drug from each class.
2. Write a brief account on the electronic & steric parameters involved in a QSAR study.
3. Classify semisynthetic pencillins.
Enumerate the mechanism of action and SAR of pencillins.
4. a) Classify sulphonamides.
Briefly discuss the mechanism of action and SAR of sulphonamides.
b) Enumerate the general synthesis of sulfonamides.
II. Write notes on: (6 x 5 = 30)
1. Discuss the life cycle of malarial parasite.
2. Describe the mechanism of action of
(a) Polyene antifungals (b) Allylamine antifungals.
3. Write a note on solid phase synthesis in combinatorial chemical library synthesis.
4. Discuss briefly on agents used for hyperthyroidism and write the structure of
any two drugs.
5. Write a note on adrenocorticoids.
6. Give the structure and uses of
(a) Chloroquine (b) Clonidine.
*******

FirstRanker.com - FirstRanker's Choice