Download Pharm D 4th Year 2015 Oct 383823 Biopharmaceutics And Pharmacokinetics Question Paper

Download Pharm-D (Doctor of Pharmacy) 4th Year (Fourth Year) 2015 Oct 383823 Biopharmaceutics And Pharmacokinetics Previous Question Paper

[LH 823] OCTOBER 2015 Sub. Code: 3823
PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FOURTH YEAR
PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS
Q.P. Code : 383823
Time: Three Hours Maximum: 70 marks
Answer ALL questions
I. Elaborate on : (4 x 10 = 40)
1. One compartment open IV bolus administration.
2. Define excretion and explain briefly about renal excretion of drugs.
3. Physiological barriers to distribution of drugs.
4. In Vitro drug dissolution testing models.
II. Write notes on : (6 x 5 = 30)
1. Approaches for dosage regimen.
2. Biopharmaceutical classification systems.
3. Line-weaver Burk plot.
4. Micro and hybrid constants.
5. Tissue localization of drugs.
6. A drug is administered at a dose of 500 mg IV bolus injection. The drug has
elimination rate constant 0.231/hr, volume of distribution is 20 L by following one
compartmental kinetics. If Area under the curve is 110 mg hr/L, then calculate mean
residence time of the drug.


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