[LK 823] MAY 2017 Sub. Code: 3823
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
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(2009-2010 Regulation)
FOURTH YEAR
PAPER V — BIOPHARMACEUTICS AND PHARMACOKINETICS
Q.P. Code : 383823
Time : Three hours Maximum : 70 Marks
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I. Elaborate on: (4 x 10 =40)
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Define drug absorption. Discuss the physiochemical factors influencing GI absorption of a drug.
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Explain briefly two compartmental open model extra Vascular Administration.
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Explain in details about pharmacokinetic and pharmacodynamic parameters.
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What are the major parameters studied in the urinary excretion data?
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II. Write notes on: (6x5=30)
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Measurement of bioavailability.
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Explain the mean residence time.
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Volume of distribution.
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Methods to enhance the bioavailability through enhancement of dissolution rate.
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How can you graphically estimate Km and Vmax from steady state concentration?
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Hepatic clearance and renal clearance.
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This download link is referred from the post: Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
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