Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
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PHARM. D/POST BACCALAUREATE DEGREE EXAMINATION (2009-2010 Regulation)
FIFTH YEAR
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PAPER III - CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING
Time : Three hours Maximum : 70 marks
- I. Elaborate on : (4 x 10 =40)
- Explain the effect of pharmacokinetics and dose adjustment in hepatic disease.
- Enumerate the various Methods of analyzing population pharmacokinetic data.
- What is pharmacodynamic interaction? Explain the consequences of direct pharmacodynamic interaction with examples.
- Explain the effect of genetic polymorphism in drug transport and drug target with example.
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- II. Write notes on : (6x5=30)
- Brief about the Inhibition of biliary excretion.
- Write a note on dosing in obese patients.
- Write the factors to be considered when designing dosage regimen.
- Enumerate the dose adjustment on drug clearance.
- Brief about therapeutic drug monitoring of seizure drugs.
- Explain the dosing with feedback.
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