Download Pharm D 5th Year 2015 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Question Paper

Download Pharm-D (Doctor of Pharmacy) 5th Year (Fifth Year) 2015 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Previous Question Paper

[LH 827] OCTOBER 2015 Sub. Code: 3827
PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FIFTH YEAR
PAPER III ? CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC
DRUG MONITORING
Q.P. Code : 383827
Time: Three Hours Maximum: 70 marks
Answer ALL questions
I. Elaborate on : (4 x 10 = 40)
1. Explain the determination of dose and dosing interval.
2. Enumerate the pharmacokinetic drug interactions with examples.
3. What is therapeutic drug monitoring? Add note on therapeutic drug monitoring
of Psychiatric Drugs and Immunosuppressants.
4. Explain the Pharmacogenetic & Nongenetic influences on Variations in Drug Therapy.
II. Write notes on : (6 x 5 = 30)
1. Brief about the dosage regimen based on population average.
2. Write the note on extra corporeal removal of the drug.
3. Discuss the adaptive method for dosing.
4. Brief the Genetic polymorphism in Drug Transport with example.
5. Describe the measurement of creatinine clearance.
6. Note on adverse drug reaction attributed to genetic differences.


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