[LM 827] MAY 2018 Sub. Code: 3827
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
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(2009-2010 Regulation)
FIFTH YEAR
PAPER III - CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING
Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks
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- I. Elaborate on: (4 x 10 =40)
- Drug dosing in elderly and paediatrics.
- Beysian theory and its application in population pharmacokinetics.
- Dosing of drugs in hepatic disease.
- What is TDM? Write about indication and protocol for TDM.
- II. Write notes on: (6x5=30)
- Methods to adjust dose for uremic patients.
- Pharmacokinetics and pharmacogenetics relation.
- Nonlinear mixed effect model.
- Extracorporeal removal of drugs.
- Determination of dose and dosing interval.
- Drug regimen for individual dosage.
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